Photobiology Unit, NHS Tayside, Ninewells Hospital & Medical School, Dundee, United Kingdom; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.
Photobiology Unit, NHS Tayside, Ninewells Hospital & Medical School, Dundee, United Kingdom.
J Invest Dermatol. 2020 Nov;140(11):2099-2104.e1. doi: 10.1016/j.jid.2020.06.033.
UVR exposure is a widely applied technique in clinical and preclinical studies. Such experimental conditions provide crucial information on the biological responses of skin and cell models, which may then be extrapolated and interpreted, for example, in the context of equivalent daylight exposures. It is therefore important to fully understand the characteristics of UVR and the principles behind correct and appropriate UVR exposure in experimental settings. In this Research Techniques Made Simple article, we discuss the relevant background information and the best practices for accurate, transparent, and reproducible experimentation and reporting of UVR exposure.
UVR 暴露是临床和临床前研究中广泛应用的技术。此类实验条件可提供有关皮肤和细胞模型生物学反应的重要信息,然后可推断并解释这些信息,例如在等效日光暴露的情况下。因此,充分了解 UVR 的特性以及在实验环境中正确和适当进行 UVR 暴露的原理非常重要。在这篇研究技术简介文章中,我们讨论了相关的背景信息,以及实现 UVR 暴露实验的准确、透明和可重现性报告的最佳实践。