Kaidbey K H, Kligman A M
J Invest Dermatol. 1981 May;76(5):352-5. doi: 10.1111/1523-1747.ep12520007.
Repeated exposures to subliminal doses of UVR, given at 24-hr intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. These findings provide quantitative evidence for the cumulative nature of acute UVR damage in human skin.
以24小时间隔重复给予阈下剂量的紫外线辐射（UVR），会导致红斑阈值剂量降低。在产生红斑等效剂量时，UV-A最有效，UV-C最无效。在重复给予阈下剂量的UV-A和局部应用8-甲氧基补骨脂素后，观察到了类似且更明显的效果。这些发现为人类皮肤急性UVR损伤的累积性质提供了定量证据。
