类固醇治疗新冠病毒肺炎伴特发性机化性肺炎样反应的疗效：一例报告。

Effectiveness of Steroid Treatment for SARS-CoV-2 Pneumonia With Cryptogenic Organizing Pneumonia-Like Reaction: A Case Report.

机构信息

Division of Pulmonology, Allergy and Critical Care Medicine, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.

Division of Infectious Disease, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.

出版信息

Disaster Med Public Health Prep. 2022 Apr;16(2):491-494. doi: 10.1017/dmp.2020.415. Epub 2020 Oct 26.

DOI:10.1017/dmp.2020.415

PMID:33100248

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7985637/

Abstract

Several studies on the treatment of coronavirus disease 2019 (COVID-19) are being conducted, and various drugs are being tried; however, the results have not been uniform. Steroids have been widely used in the treatment of COVID-19, but their effects are controversial. As immunosuppressive and anti-inflammatory agents, steroids are considered to reduce lung damage by regulating various inflammatory responses. We report a case of severe acute respiratory syndrome coronavirus-2 pneumonia manifesting as a cryptogenic organizing pneumonia-like reaction and discuss its treatment, clinical course, and favorable outcomes after steroid administration.

摘要

目前正在进行多项关于 2019 冠状病毒病（COVID-19）治疗的研究，尝试了各种药物，但结果并不一致。皮质类固醇在 COVID-19 的治疗中被广泛应用，但疗效存在争议。作为免疫抑制剂和抗炎药，皮质类固醇被认为通过调节各种炎症反应来减轻肺损伤。我们报告了一例严重急性呼吸综合征冠状病毒 2 肺炎表现为隐源性机化性肺炎样反应的病例，并讨论了其治疗、临床经过以及皮质类固醇治疗后的良好结局。