Geethapriya Sivaramalingam, Govindaraj Jayaraj, Raghavan Bagyam, Ramakrishnan Banupriya, Arafath Rasheed, Vishwanathan Sathyashree, Krishna Murali
Department of Radiology, Apollo Cancer Institutes, Padma Complex, Anna Salai, Chennai, Tamil Nadu, India.
Indian J Radiol Imaging. 2020 Apr-Jun;30(2):116-125. doi: 10.4103/ijri.IJRI_17_20. Epub 2020 Jul 13.
Schwannomas are peripheral nerve sheath tumours arising from cranial, spinal or peripheral nerves. Most of the schwannomas are benign with the rare possibility of malignant transformation. Cranial nerve schwannomas can be seen along the course of any cranial nerve in the intracranial region or head and neck location. Although a majority are solitary sporadic lesions, multiple schwannomas can be seen in syndromes like neurofibromatosis type 2 and rarely in type 1. Since intracranial schwannomas are slow-growing, clinical presentation varies between no symptoms to cranial nerve palsy. Most of the times, the symptoms are due to mass effect over the adjacent structures, foraminal widening, compression of other cranial nerves, denervation injury or hydrocephalus. Familiarity with the course of the cranial nerves, imaging appearances and clinical presentation of schwannomas helps in accurate diagnosis and possible differential diagnosis, especially in uncommon clinical and radiological appearances. In this pictorial review, we illustrate relevant anatomy of cranial nerves, imaging features of schwannomas of most of the cranial nerves, clinical presentation and differential diagnosis.
施万细胞瘤是起源于颅神经、脊神经或周围神经的周围神经鞘瘤。大多数施万细胞瘤是良性的,恶变的可能性很小。颅内神经鞘瘤可出现在颅内区域或头颈部任何颅神经走行部位。虽然大多数是孤立性散发病变,但在2型神经纤维瘤病综合征中可出现多发施万细胞瘤,在1型中则很少见。由于颅内施万细胞瘤生长缓慢,临床表现从无症状到颅神经麻痹不等。大多数情况下,症状是由于对相邻结构的占位效应、孔道增宽、对其他颅神经的压迫、去神经损伤或脑积水所致。熟悉颅神经走行、施万细胞瘤的影像学表现和临床表现有助于准确诊断及可能的鉴别诊断,尤其是在不常见的临床和影像学表现时。在本图片综述中,我们展示了颅神经的相关解剖结构、大多数颅神经施万细胞瘤的影像学特征、临床表现及鉴别诊断。