替格瑞洛相关性严重呼吸困难：机制、特征、鉴别诊断与治疗
Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment.
作者信息
Krakowiak Alicja, Kuleta Jakub, Plech Iwona, Zarębiński Maciej, Wojciechowska Małgorzata, Wretowski Dominik, Cudnoch-Jędrzejewska Agnieszka
机构信息
Department of Experimental and Clinical Physiology, Laboratory of Center for Preclinical Research, Medical University of Warsaw, Warsaw, Poland.
Invasive Cardiology Unit, Independent Public Specialist Western Hospital John Paul II in Grodzisk Mazowiecki, Poland.
出版信息
Clin Med Insights Case Rep. 2020 Oct 8;13:1179547620956634. doi: 10.1177/1179547620956634. eCollection 2020.
With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these complications, explain how to carry out differential diagnosis, discuss when to switch ticagrelor to other antiplatelet drug and finally we present the way to deal with the symptoms.
随着支架植入术后接受替格瑞洛治疗的患者数量不断增加，我们观察到许多该药物的副作用病例，主要是呼吸困难和心动过缓。在我们的文章中，我们介绍了2例症状特别严重的患者。然后我们描述了这些并发症的可能机制，解释了如何进行鉴别诊断，讨论了何时将替格瑞洛换为其他抗血小板药物，最后我们介绍了应对这些症状的方法。
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