Paterno Jennifer, Petrillo Alessandra, Dicapua Siegel David Samuel, Ogedegbe Chinwe
Hackensack University Medical Center, 30 Prospect Ave, Hackensack, NJ, USA.
Case Rep Hematol. 2020 Oct 10;2020:8823908. doi: 10.1155/2020/8823908. eCollection 2020.
This case presents a patient with bacteremia of an unusual organism with a history of monoclonal gammopathy of undetermined significance (MGUS). MGUS is typically thought to be asymptomatic until potential progression of the disease. This case reports a patient with a history of MGUS who does not show disease progression, however, may be showing symptoms, such as immunodeficiency. This case displays bacteremia with within a two-week period of an invasive procedure. Recent studies parallel this case by showing MGUS patients may have two times the risk of infections compared to the unaffected population. This report brings up the question of taking prophylactic measures for this patient population to prevent future complications.
该病例报告了一名患有意义未明的单克隆丙种球蛋白病（MGUS）病史的患者，其感染了一种不常见的病原体导致菌血症。MGUS通常被认为在疾病潜在进展之前是无症状的。本病例报告了一名有MGUS病史的患者，该患者虽未出现疾病进展，但可能表现出免疫缺陷等症状。此病例显示在侵入性操作后的两周内发生了菌血症。近期研究表明MGUS患者发生感染的风险可能是未受影响人群的两倍，与该病例情况相似。本报告提出了是否应为该患者群体采取预防措施以防止未来并发症的问题。
