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癫痫发作和癫痫的当前分类:范围、局限性及未来行动建议

Current Classification of Seizures and Epilepsies: Scope, Limitations and Recommendations for Future Action.

作者信息

Sarmast Shah T, Abdullahi Abba Musa, Jahan Nusrat

机构信息

Neurology, California Institute of Behavioral Neuroscience & Psychology, Fairfield, USA.

Neurology/Neuroscience, California Institute of Behavioral Neuroscience & Psychology, Fairfield, USA.

出版信息

Cureus. 2020 Sep 20;12(9):e10549. doi: 10.7759/cureus.10549.

Abstract

The classification of seizures and epilepsies by the International League Against Epilepsy (ILAE), 2017 is the most recent classification model which aimed to simplify terminologies that patients and their caregivers can easily understand, identify seizures that have both focal and generalized onset and incorporate missing seizures. We have exhaustively reviewed the studies, discussed its scope, outlined its limitations and gave recommendations that could help in forming subsequent reviews. We have also described the terminologies that have been replaced, redefined or removed to have a clear view of the previous and the current classification models. We have recommended the use of multidimensional classification model which incorporated the clinical semiology, disease location, etiology and associated comorbidities. The benefits of this model is for prompt diagnosis which will results into early management and then better patient outcomes. It would also have a profound effects on the kind of treatment patients might receive especially in developing countries where there are scarcity of the diagnostic techniques. Overall, in this study we have reviewed the current study on seizures and epilepsy classification model by ILAE, 2017 to clarify the descriptions and coverage, outlined some limitations and suggested recommendations.

摘要

国际抗癫痫联盟(ILAE)2017年发布的癫痫发作和癫痫分类是最新的分类模型,旨在简化患者及其护理人员易于理解的术语,识别既有局灶性发作又有全面性发作的癫痫发作类型,并纳入遗漏的发作类型。我们详尽回顾了相关研究,讨论了其范围,概述了其局限性,并给出了有助于形成后续综述的建议。我们还描述了已被取代、重新定义或删除的术语,以便清楚地了解先前和当前的分类模型。我们建议使用纳入临床症状学、疾病部位、病因及相关合并症的多维分类模型。该模型的好处是能实现快速诊断,从而进行早期管理并带来更好的患者预后。它还会对患者可能接受的治疗类型产生深远影响,尤其是在诊断技术匮乏的发展中国家。总体而言,在本研究中我们回顾了ILAE 2017年关于癫痫发作和癫痫分类模型的当前研究,以阐明其描述和涵盖范围,概述一些局限性并提出建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c2/7575300/6ad76a327a4f/cureus-0012-00000010549-i01.jpg

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