Claro-Almea Franklin E, Delgado-Noguera Lourdes A, Motaban Ana, España Mercedes, de Waard Jacobus H
Servicio Autónomo Instituto de Biomedicina Dr. Jacinto Convit, Universidad Central de Venezuela, Caracas, Venezuela.
Infectious Diseases Division, Venezuelan Research Incubator and the Zoonosis and Emerging Pathogens Regional Collaborative Network, Barquisimeto, Venezuela.
IDCases. 2020 Oct 6;22:e00982. doi: 10.1016/j.idcr.2020.e00982. eCollection 2020.
We report a rare presentation of Pott's disease caused by suggesting transmission from infected cattle, and only the second case described so far in scientific reports. Noteworthy of this case was that the strain was only isolated on Stonebrink medium, a sodium pyruvate-containing culture medium for the isolation of mycobacteria. This medium is frequently ignored in diagnostic laboratories and in the laboratory manuals of most international health organizations. In general laboratories use a culture medium that contains glycerol, a carbon substrate considered inhibitory for the growth of . The use of glycerol-containing medium therefore likely contributes towards underestimating zoonotic tuberculosis. Our case suggests that, in order to improved surveillance efforts for zoonotic TB and increase the notification rate for to human TB, the use of pyruvate-containing media should be promoted, particularly in developing countries with a high prevalence of bovine TB, but also through the World Health Organization' (WHO) and the .
我们报告了一例罕见的波特氏病病例，病因提示为感染牛的传播，这也是迄今为止科学报告中描述的第二例。该病例值得注意的是，该菌株仅在斯通布林克培养基上分离出来，这是一种用于分离分枝杆菌的含丙酮酸钠的培养基。在诊断实验室和大多数国际卫生组织的实验室手册中，这种培养基经常被忽视。一般来说，实验室使用的培养基含有甘油，一种被认为对[具体分枝杆菌名称未给出]生长有抑制作用的碳底物。因此，使用含甘油的培养基可能导致人畜共患结核病被低估。我们的病例表明，为了加强对人畜共患结核病的监测力度并提高[具体分枝杆菌名称未给出]向人类结核病的报告率，应推广使用含丙酮酸钠的培养基，特别是在牛结核病高发的发展中国家，同时也应通过世界卫生组织（WHO）以及[具体组织名称未给出]来推广。
