El Achi Nassim, Bakkour Youssef, Adhami Wissal, Molina Julien, Penhoat Maël, Azaroual Nathalie, Chausset-Boissarie Laëtitia, Rolando Christian
MSAP 'Miniaturisation pour la Synthèse l'Analyse et la Protéomique', Université de Lille, USR CNRS 3290, Lille, France.
Laboratory of Applied Chemistry, Faculty of Sciences III, Lebanese University, Tripoli, Lebanon.
Front Chem. 2020 Sep 8;8:740. doi: 10.3389/fchem.2020.00740. eCollection 2020.
ATRP of methyl methacrylate catalyzed by Eosin Y, an inexpensive and an environmental benign dye, was performed in a continuous flow reactor made of FEP tubing and irradiated by visible light green LEDs. The reaction under flow conditions was significantly more rapid and controlled compared to that in batch giving 90% of polymerization after only 3 h of irradiation. The formed polymers in flow have measured by GPC and DOSY NMR in accordance with the theoretical values and show low dispersities (Ð < 1.5). The livingness of the polymers has been confirmed by LED on and LED off experiments and by the synthesis of block copolymers. The protocol described herein serves as a "proof of concept" of using Eosin Y as a photocatalyst for controlled polymerization and of using 1D and 2D NMR for polymer characterization. The protocol could be replicated in the future for other reversible-deactivation radical polymerizations.
以曙红Y（一种廉价且环境友好的染料）为催化剂，在由氟塑料（FEP）管制成并由可见光绿色发光二极管（LED）照射的连续流动反应器中进行甲基丙烯酸甲酯的原子转移自由基聚合（ATRP）。与间歇反应相比，流动条件下的反应明显更快且更可控，仅照射3小时后就有90%的聚合反应发生。流动状态下形成的聚合物已通过凝胶渗透色谱（GPC）和扩散排序核磁共振（DOSY NMR）进行测量，结果与理论值相符，且分散度较低（Ð < 1.5）。通过发光二极管开启和关闭实验以及嵌段共聚物的合成，证实了聚合物的活性。本文所述方案是使用曙红Y作为可控聚合的光催化剂以及使用一维和二维核磁共振进行聚合物表征的“概念验证”。未来该方案可用于其他可逆失活自由基聚合反应。
