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结核性胸腔积液中的腺苷脱氨酶活性:一种诊断检测方法。

Adenosine deaminase activity in tuberculous pleural effusions: a diagnostic test.

作者信息

Strankinga W F, Nauta J J, Straub J P, Stam J

机构信息

Department of Pulmonology and Tuberculosis, Academic Hospital, Free University, Amsterdam, The Netherlands.

出版信息

Tubercle. 1987 Jun;68(2):137-40. doi: 10.1016/0041-3879(87)90029-8.

Abstract

The activity of adenosine deaminase (ADA) was investigated in pleural effusions from 10 patients with tuberculous pleurisy and 76 patients with pleural effusions of other aetiology. The ADA activity in the tuberculous patients was significantly higher than in the other groups, with the exception of those with empyema. Specificity (87%) and sensitivity (100%) of this test for tuberculosis is high when a reference limit of more than 53 U/l is taken.

摘要

对10例结核性胸膜炎患者及76例其他病因所致胸腔积液患者的胸腔积液中的腺苷脱氨酶(ADA)活性进行了研究。除脓胸患者外,结核患者的ADA活性显著高于其他组。当参考限值设定为超过53 U/l时,该检测对结核病的特异性(87%)和敏感性(100%)较高。

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