使用腺苷脱氨酶作为结核性胸膜炎的诊断工具。
Use of adenosine deaminase as a diagnostic tool for tuberculous pleurisy.
作者信息
Burgess L J, Maritz F J, Le Roux I, Taljaard J J
机构信息
Department of Chemical Pathology, University of Stellenbosch, Tygerberg Hospital, South Africa.
出版信息
Thorax. 1995 Jun;50(6):672-4. doi: 10.1136/thx.50.6.672.
Abstract
BACKGROUND
A statistical audit of adenosine deaminase (ADA) in pleural effusions was undertaken.
METHODS
ADA analysis, cytological and microbiological examinations, and differential cell counts were performed on 462 pleural fluid samples.
RESULTS
ADA activity in tuberculous effusions was higher than in any other diagnostic group. At a level of 50 U/l the sensitivity and specificity for the identification of tuberculosis was 90% and 89%, respectively.
CONCLUSIONS
ADA activity remains a useful test in the evaluation of pleural effusions.
摘要
背景
对胸腔积液中的腺苷脱氨酶（ADA）进行了统计分析。
方法
对462份胸腔积液样本进行了ADA分析、细胞学和微生物学检查以及细胞分类计数。
结果
结核性胸腔积液中的ADA活性高于其他任何诊断组。ADA水平为50 U/l时，诊断结核病的敏感性和特异性分别为90%和89%。
结论
ADA活性在胸腔积液评估中仍然是一项有用的检测。
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本文引用的文献
1
Diagnosis of tuberculous pleurisy using the biologic parameters adenosine deaminase, lysozyme, and interferon gamma.利用生物参数腺苷脱氨酶、溶菌酶和干扰素γ诊断结核性胸膜炎。
Chest. 1993 Feb;103(2):458-65. doi: 10.1378/chest.103.2.458.
2
Adenosine deaminase estimations in the differentiation of pleural effusions.腺苷脱氨酶测定在胸腔积液鉴别诊断中的应用
S Afr Med J. 1982 Oct 9;62(16):556-8.
3
Adenosine deaminase in pleural fluids. Test for diagnosis of tuberculous pleural effusion.胸腔积液中的腺苷脱氨酶。用于结核性胸腔积液诊断的检测。
Chest. 1983 Jul;84(1):51-3. doi: 10.1378/chest.84.1.51.
4
Diagnostic significance of lymphocytes in pleural effusions.胸腔积液中淋巴细胞的诊断意义
Ann Intern Med. 1967 May;66(5):972-82. doi: 10.7326/0003-4819-66-5-972.
5
Tuberculous pleurisy.结核性胸膜炎
Chest. 1973 Jan;63(1):88-92. doi: 10.1378/chest.63.1.88.
6
The use of relative operating characteristic (ROC) curves in test performance evaluation.相对操作特征（ROC）曲线在测试性能评估中的应用。
Arch Pathol Lab Med. 1986 Jan;110(1):13-20.
7
Adenosine deaminase activity, not diagnostic for tuberculous pleurisy.腺苷脱氨酶活性，对结核性胸膜炎无诊断意义。
Eur J Respir Dis. 1987 Jul;71(1):15-8.
8
Adenosine deaminase activity in tuberculous pleural effusions: a diagnostic test.结核性胸腔积液中的腺苷脱氨酶活性：一种诊断检测方法。
Tubercle. 1987 Jun;68(2):137-40. doi: 10.1016/0041-3879(87)90029-8.
9
State of the art. The pleura.前沿技术。胸膜。
Am Rev Respir Dis. 1988 Jul;138(1):184-234. doi: 10.1164/ajrccm/138.1.184.
10
Diagnostic procedures for pleural disease.胸膜疾病的诊断程序。
Clin Chest Med. 1985 Mar;6(1):33-48.
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