LIFE Leipzig Research Center for Civilization Diseases, Leipzig University, Leipzig, Germany.
Department of Women and Child Health, University Hospital for Children and Adolescents and Center for Pediatric Research, Leipzig University, Leipzig, Germany.
Ophthalmic Physiol Opt. 2021 Jan;41(1):42-52. doi: 10.1111/opo.12748. Epub 2020 Oct 26.
This study describes the prevalence of visual impairment caused by uncorrected distance refractive error and the spectacle coverage in a large cohort of German children and adolescents. Furthermore, we determined the prevalence of amblyopia and amblyopia treatment.
Optometrists carried out visual acuity (VA) testing, non-cycloplegic autorefraction, VA retesting with the refractive correction obtained by autorefraction, and if necessary subjective refraction and cover-test in 1,874 subjects (901 girls/973 boys), aged 3 to 16 years. Additionally, a questionnaire on the history of previous eye care was completed.
Distance visual impairment (VI) with VA worse than 6/18 Snellen in the better eye was present in 0.5% (95% confidence interval [95% CI]: 0.2% to 0.9%) of children. Logistic regression showed a significant positive association between VI and older age (OR = 1.21, P = 0.03). Gender differences were not found (P = 0.77). The spectacle coverage of all participants was 74.8% (95% CI: 65.2% to 82.8%). Amblyopia was found in 29 participants (1.5%; 95% CI: 1.0% to 2.2%) with no age or sex differences. The causes of unilateral amblyopia (27 cases, 93.1%) were anisometropia in 55.6% of children, strabismus in 25.9% and the combination of these factors in 18.5%. All children with bilateral amblyopia (2 cases, 6.9%) showed bilateral high ametropia. We observed 15 children with current amblyopia, who had been treated with occlusion therapy in the past (62.2%; 95% CI: 42.7% to 83.6%).
The prevalence of impaired VA caused by uncorrected refractive error and amblyopia is comparable with previous studies conducted in urban areas worldwide. Adding the measurement of refractive error to existing medical check-ups, possibly using autorefraction, would be desirable.
本研究描述了未经矫正的远距离屈光不正导致的视力障碍以及大量德国儿童和青少年的眼镜覆盖率。此外,我们还确定了弱视和弱视治疗的患病率。
验光师对 1874 名 3 至 16 岁的受试者(901 名女孩/973 名男孩)进行了视力(VA)测试、非睫状肌自动折射、VA 复测(使用自动折射获得的屈光矫正),如有必要还进行了主观折射和遮盖试验,并完成了一份关于既往眼部护理史的调查问卷。
在较好的眼睛中,VA 低于 6/18 Snellen 的远距离视力障碍(VI)在 0.5%(95%置信区间[95%CI]:0.2%至 0.9%)的儿童中存在。逻辑回归显示 VI 与年龄较大呈显著正相关(OR=1.21,P=0.03)。未发现性别差异(P=0.77)。所有参与者的眼镜覆盖率为 74.8%(95%CI:65.2%至 82.8%)。29 名儿童(1.5%;95%CI:1.0%至 2.2%)被诊断为弱视,无年龄或性别差异。27 例(93.1%)单侧弱视的原因是屈光参差,55.6%的儿童有斜视,25.9%的儿童有这些因素的组合,18.5%的儿童有这些因素的组合。所有双侧弱视的儿童(2 例,6.9%)均表现为双侧高度屈光不正。我们观察到 15 名患有当前弱视的儿童,他们过去曾接受过遮盖治疗(62.2%;95%CI:42.7%至 83.6%)。
未经矫正的屈光不正和弱视导致的视力障碍患病率与全球城市地区以前的研究相当。在现有的医疗检查中增加屈光不正的测量,可能使用自动折射,是可取的。