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双筒肠成形术治疗儿童短肠综合征。

Double barrel enteroplasty for the management of short bowel syndrome in children.

机构信息

Department of Paediatric Surgery, The Children's Hospital at Westmead, Westmead, NSW, Australia.

Discipline of Child and Adolescent Health, The University of Sydney, Sydney, NSW, Australia.

出版信息

Pediatr Surg Int. 2021 Jan;37(1):169-177. doi: 10.1007/s00383-020-04767-0. Epub 2020 Oct 26.

Abstract

BACKGROUND

Currently, there are two well-established methods of bowel lengthening in patients with short bowel syndrome (SBS)-longitudinal intestinal lengthening and tailoring (LILT) and serial transverse enteroplasty (STEP) [1-4]. Both procedures may carry a high reported morbidity and mortality of 30.2% and 14.4%, respectively [5]. We report the outcomes of a novel technique: double barrel enteroplasty (DBE) for autologous intestinal reconstruction.

METHODS

We performed a retrospective review of all ten patients who underwent DBE at our institution since 2011. All patients have SBS and were dependent on parenteral nutrition (PN) at the time of surgery. Etiologies were gastroschisis (n = 4), bowel atresia (n = 3), necrotising enterocolitis (n = 1), volvulus (n = 1), and near-total intestinal aganglionosis (n = 1). Patient survival, complications, and subsequent enteral autonomy were evaluated.

RESULTS

All patients are alive with normal liver function. Five children achieved enteral autonomy, while the remaining are on weaning PN. There was no bleeding, anastomotic leak, perforation, infective complications, or intestinal necrosis. No patient has required a liver and/or intestinal transplant.

CONCLUSIONS

Double barrel enteroplasty is technically feasible and safe. It has similar efficacy and may have fewer complications when compared with other methods of autologous intestinal reconstruction.

摘要

背景

目前,治疗短肠综合征(SBS)有两种成熟的肠延长方法——纵向肠延长和裁剪术(LILT)和连续横向肠成形术(STEP)[1-4]。这两种手术的报道发病率和死亡率均较高,分别为 30.2%和 14.4%[5]。我们报告了一种新的技术:双桶肠成形术(DBE)在自体肠重建中的应用结果。

方法

我们对 2011 年以来在我院接受 DBE 的 10 例患者进行了回顾性分析。所有患者均患有 SBS,且在手术时依赖于肠外营养(PN)。病因包括先天性腹裂(n=4)、肠闭锁(n=3)、坏死性小肠结肠炎(n=1)、肠扭转(n=1)和全层肠壁无神经节细胞症(n=1)。评估了患者的存活率、并发症和随后的肠内自主能力。

结果

所有患者均存活,肝功能正常。5 例患儿实现了肠内自主,其余患儿正在逐渐减少 PN。无出血、吻合口漏、穿孔、感染并发症或肠坏死。无患者需要进行肝和/或肠移植。

结论

双桶肠成形术技术上是可行且安全的。与其他自体肠重建方法相比,它具有相似的疗效,且并发症可能更少。

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