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常压性脑积水和 CSF 引流试验反应：步态表型很重要。

Normal pressure hydrocephalus and CSF tap test response: the gait phenotype matters.

机构信息

Department of Neurology, University Clinic of Neurology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 16, 3010, Bern, Switzerland.

Faculty of Medicine, University Geneva Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, Switzerland.

出版信息

J Neural Transm (Vienna). 2021 Jan;128(1):121-125. doi: 10.1007/s00702-020-02270-3. Epub 2020 Oct 26.

DOI:10.1007/s00702-020-02270-3
PMID:33106967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7815574/
Abstract

This study compared gait speed changes after CSF tap test in patients with idiopathic normal pressure hydrocephalus presenting with various gait phenotypes (frontal, parkinsonian, normal, or other). All patients improved, except those with parkinsonian gait.

摘要

本研究比较了具有不同步态表型（额状面型、帕金森型、正常型或其他型）的特发性正常压力脑积水患者行腰穿脑脊液引流术后步态速度的变化。所有患者均有改善，除帕金森步态患者外。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df8/7815574/648a7f300219/702_2020_2270_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df8/7815574/648a7f300219/702_2020_2270_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df8/7815574/648a7f300219/702_2020_2270_Fig1_HTML.jpg

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本文引用的文献

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2
Parkinsonism is a Phenotypical Signature of Amyloidopathy in Patients with Gait Disorders.帕金森病是步态障碍患者淀粉样变的表型特征。
J Alzheimers Dis. 2018;63(4):1373-1381. doi: 10.3233/JAD-171055.
3
A combined cognitive and gait quantification to identify normal pressure hydrocephalus from its mimics: The Geneva's protocol.一种结合认知与步态量化以从其模仿病症中识别正常压力脑积水的方法：日内瓦方案
特发性正常压力脑积水的步态特征：脑脊液穿刺试验和分流手术效果综述
Eur J Med Res. 2024 Dec 30;29(1):633. doi: 10.1186/s40001-024-02162-2.
4
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Eur J Neurol. 2024 Aug;31(8):e16328. doi: 10.1111/ene.16328. Epub 2024 May 8.
5
[A gait signal acquisition and parameter characterization method based on foot pressure detection combined with Azure Kinect system].一种基于足部压力检测与Azure Kinect系统相结合的步态信号采集与参数表征方法
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2023 Apr 25;40(2):350-357. doi: 10.7507/1001-5515.202210026.
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INPH and parkinsonism: A positive shunt response with a negative tap test.正常压力脑积水与帕金森综合征：分流试验阳性而叩诊试验阴性。
Front Neurol. 2023 Mar 29;14:1150258. doi: 10.3389/fneur.2023.1150258. eCollection 2023.
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