从软珊瑚来源真菌 sp. SCSIO 041201 中分离得到的两个新的生物活性多酚。
Two new bioactive polyphenols from the soft coral-derived fungus sp. SCSIO 041201.
机构信息
Pharmacy School of Guilin Medical University, Guilin Medical University, Guilin, P. R. China.
Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou P. R. China.
出版信息
Nat Prod Res. 2021 Dec;35(24):5778-5785. doi: 10.1080/14786419.2020.1836632. Epub 2020 Oct 27.
Two new polyphenols, talaversatilis A () and B (), together with fifteen known compounds (-) were isolated from the extract of the culture broth of a soft coral-derived fungus sp. SCSIO 041201. The structures of these compounds were elucidated by the extensive analyses of spectroscopic data and by comparison with the reported literature. Antifouling and antibacterial activities of all purified compounds were tested and evaluated. Compounds and showed antifouling activity towards larva, with LC values of 3.86 μg/mL and 3.05 μg/mL, respectively. Compounds , , and exhibited significant antibacterial activities against , , and , with MIC values ranging from 0.45 to 15.6 μg/mL.
从软珊瑚来源真菌 sp. SCSIO 041201 的发酵液提取物中分离得到两种新的多酚化合物 talaversatilis A () 和 B ()，以及十五种已知化合物 (-)。通过广泛的光谱数据分析和与文献报道的比较，解析了这些化合物的结构。测试和评估了所有纯化化合物的抗污和抗菌活性。化合物 和 对 幼虫表现出抗污活性，LC 值分别为 3.86 μg/mL 和 3.05 μg/mL。化合物 、 、 和 对 、 、 和 表现出显著的抗菌活性，MIC 值范围为 0.45 至 15.6 μg/mL。
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