Division of Cardiology and Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University , Chongqing, China.
Electromagn Biol Med. 2021 Jan 2;40(1):138-149. doi: 10.1080/15368378.2020.1839490. Epub 2020 Oct 27.
The biological effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure are not fully clarified. We conducted this investigation to explore the effects of ELF-EMF on hematologic and biochemical indexes in adult rats. Thirty adult male Sprague-Dawley rats were exposed to ELF-EMF at 1 mT for 24 weeks, while another 30 SD rats were sham exposed. During the exposure, peripheral blood was collected every 4 weeks to analyze the hematologic parameters and biochemical indexes. The morphology of liver and kidney was detected by hematoxylin-eosin staining at the end of the experiment. Exposed to ELF-EMF at 1 mT did not exert any statistic difference on hematologic parameters including total white blood cell count, neutrophil ratio, lymphocyte ratio, red blood cells, hemoglobin concentration and platelets count, compared to the control group. Similarly, biochemical indexes, such as glucose, lipid profile, liver function and renal function, were not affected by ELF-EMF exposure. In addition, no morphological change was observed in the liver and kidney from the exposure group. The exposure to ELF-EMF at the intensity of 1 mT for 24 weeks did not affect hematologic and biochemical indexes in adult rats.
极低频电磁场（ELF-EMF）暴露的生物学效应尚未完全阐明。我们进行了这项研究，以探讨 ELF-EMF 对成年大鼠血液学和生化指标的影响。将 30 只成年雄性 Sprague-Dawley 大鼠暴露于 1 mT 的 ELF-EMF 中 24 周，而另外 30 只 SD 大鼠则进行假暴露。在暴露期间，每 4 周采集外周血，以分析血液学参数和生化指标。实验结束时，通过苏木精-伊红染色检测肝、肾形态。与对照组相比，暴露于 1 mT 的 ELF-EMF 对包括白细胞总数、中性粒细胞比例、淋巴细胞比例、红细胞、血红蛋白浓度和血小板计数在内的血液学参数没有任何统计学差异。同样，血糖、血脂谱、肝功能和肾功能等生化指标也不受 ELF-EMF 暴露的影响。此外，从暴露组观察到肝和肾没有形态变化。在 24 周内以 1 mT 的强度暴露于 ELF-EMF 不会影响成年大鼠的血液学和生化指标。
