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使用两种不同低雌激素组合进行两年口服避孕期间的血浆肾素活性、血压和体重

Plasma renin activity, blood pressure and body weight during two years' oral contraception with two different low-estrogen combinations.

作者信息

Liukko P, Erkkola R, Grönroos M, Lammintausta R

机构信息

Department of Obstetrics and Gynecology, University Central Hospital, Turku, Finland.

出版信息

Ann Chir Gynaecol Suppl. 1987;202:50-3.

PMID:3310827
Abstract

Body weight, systolic and diastolic blood pressure and plasma renin activity (PRA) were longitudinally followed in two groups of women during 2 years' oral contraception. One group (n = 10) received a combination of 0.150 mg levonorgestrel plus 0.030 mg ethinyloestradiol and the other (n = 10) a combination of 0.150 mg desogestrel plus 0.030 mg ethinyloestradiol. Three subjects discontinued the study due to relocation. No statistically significant changes occurred in any of the measured parameters.

摘要

在两组女性口服避孕药的两年期间,对其体重、收缩压和舒张压以及血浆肾素活性(PRA)进行了纵向跟踪。一组(n = 10)服用0.150毫克左炔诺孕酮加0.030毫克炔雌醇的组合,另一组(n = 10)服用0.150毫克去氧孕烯加0.030毫克炔雌醇的组合。三名受试者因搬迁而退出研究。所测量的任何参数均未发生统计学上的显著变化。

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Ann Chir Gynaecol Suppl. 1987;202:50-3.
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引用本文的文献

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The impact of progestogens on RAAS - a systematic review.孕激素对肾素-血管紧张素-醛固酮系统的影响——一项系统评价
BMC Womens Health. 2025 Feb 22;25(1):81. doi: 10.1186/s12905-025-03587-5.
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Combination contraceptives: effects on weight.复方避孕药:对体重的影响。
Cochrane Database Syst Rev. 2014 Jan 29;2014(1):CD003987. doi: 10.1002/14651858.CD003987.pub5.