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点状掌跖角化病。定居微球菌的作用。

Pitted keratolysis. The role of Micrococcus sedentarius.

作者信息

Nordstrom K M, McGinley K J, Cappiello L, Zechman J M, Leyden J J

机构信息

Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia 19104.

出版信息

Arch Dermatol. 1987 Oct;123(10):1320-5. doi: 10.1001/archderm.123.10.1320.

Abstract

Though pitted keratolysis of the foot is generally viewed to be caused by bacteria, there is confusion regarding the identity of the causative organism. Species of Corynebacterium, Actinomyces, Dermatophilus, and Micrococcus have been proposed by various investigators. We have studied eight cases of pitted keratolysis and have cultured an organism identified as Micrococcus sedentarius on the basis of colonial morphology, micromorphology, biochemical reactions, and chemical analysis of whole-cell components. Furthermore, pitted keratolysis was produced experimentally in a human volunteer by applying M sedentarius under an occlusive dressing onto the surface of the heel.

摘要

虽然足部凹坑状角质松解症通常被认为是由细菌引起的,但对于致病微生物的身份存在混淆。不同的研究者提出了棒状杆菌属、放线菌属、嗜皮菌属和微球菌属的细菌。我们研究了8例凹坑状角质松解症病例,并根据菌落形态、微观形态、生化反应和全细胞成分的化学分析,培养出一种被鉴定为定居微球菌的微生物。此外,通过在一名人类志愿者的足跟表面封闭敷用定居微球菌,在实验中引发了凹坑状角质松解症。

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