Kushwaha Sonam, Singh Shivendra Kumar, Manar Manish, Verma Ajay Kumar, Kar Sujita Kumar, Gupta Abhishek
Department of Community Medicine and Public Health, King George's Medical University, Lucknow, Uttar Pradesh, India.
Department of Respiratory Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
J Family Med Prim Care. 2020 Aug 25;9(8):4074-4078. doi: 10.4103/jfmpc.jfmpc_457_20. eCollection 2020 Aug.
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by the presence of persistent respiratory symptoms and airflow limitation due to airway and/or alveolar abnormalities owing to significant exposure to noxious particles or gases. Restricted activities of daily living as a result of reduced pulmonary function or dyspnea, impair quality of life in such patients.
A cross-sectional study was conducted in a tertiary care hospital of Lucknow with 250 COPD patients to assess their health-related quality of life (HRQOL) using the St. Georges Respiratory Questionnaire (SGRQ). Study participants were selected using a systematic random sampling method.
HRQOL of participants was significantly impaired. Employment status and airflow limitation severity of study participants had a statistically significant negative correlation whereas, duration since diagnosis of disease was seen to have a statistically significant positive correlation with SGRQ scores.
COPD deteriorated the quality of life of patients. The activity score was the most affected. Urban residents had a comparatively poor HRQOL.
慢性阻塞性肺疾病（COPD）是一种慢性呼吸道疾病，其特征为由于大量接触有害颗粒或气体导致气道和/或肺泡异常，从而出现持续的呼吸道症状和气流受限。肺功能下降或呼吸困难导致的日常生活活动受限，会损害此类患者的生活质量。
在勒克瑙的一家三级护理医院对250名慢性阻塞性肺疾病患者进行了一项横断面研究，使用圣乔治呼吸问卷（SGRQ）评估他们的健康相关生活质量（HRQOL）。研究参与者采用系统随机抽样方法选取。
参与者的健康相关生活质量显著受损。研究参与者的就业状况与气流受限严重程度呈统计学显著负相关，而自疾病诊断以来的持续时间与圣乔治呼吸问卷得分呈统计学显著正相关。
慢性阻塞性肺疾病使患者的生活质量恶化。活动评分受影响最大。城市居民的健康相关生活质量相对较差。
