Choudhuri Ananya, Raphael Vandana, Dey Biswajit, Khonglah Yookarin, Mishra Jaya, Marbaniang Evarisalin
Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.
J Family Med Prim Care. 2020 Aug 25;9(8):4205-4209. doi: 10.4103/jfmpc.jfmpc_656_20. eCollection 2020 Aug.
Mediastinal masses are uncommon in clinical practice. Fine-needle aspiration cytology (FNAC) is an important and useful investigation and is considered next to imaging in the diagnosis of mediastinal lesions.
To analyze the mediastinal masses diagnosed on FNAC.
We retrospectively retrieved twenty-five cases, which underwent FNAC under ultrasound or computed tomography (CT) guidance for mediastinal masses, over a period of 4 years. Histopathological correlations were done in cases wherever available.
Among twenty-five cases, which were diagnosed through FNAC, eighteen were males and seven were females with age ranging from 6 to 85 years. Ultrasonography (USG)-guided FNAC was performed in three patients, while CT-guided FNAC was performed in twenty-two patients. Out of twenty-five cases, seventeen cases were malignant, six were benign, and two cases were inadequate. FNAC was useful in the diagnosis of 83.3% of cases. Biopsy and/or cell block correlations were available in fourteen cases. In the malignant category, mediastinal invasion by either squamous cell carcinoma or adenocarcinoma constituted the highest number with eight (47%) out of seventeen cases. Among the nonneoplastic conditions, nonspecific inflammation was the most common cause with two cases (8%) out of total cases followed by one case each of tuberculosis, schwannoma, thymoma, and cystic lesion.
USG or CT-guided FNAC is a safe, minimally invasive, and cost-effective procedure, which can provide a precise diagnosis in the mediastinal masses, and may obviate the need for an invasive surgical approach.
纵隔肿物在临床实践中并不常见。细针穿刺细胞学检查（FNAC）是一项重要且有用的检查，在纵隔病变的诊断中仅次于影像学检查。
分析通过FNAC诊断的纵隔肿物。
我们回顾性检索了25例患者，这些患者在4年期间因纵隔肿物在超声或计算机断层扫描（CT）引导下接受了FNAC检查。尽可能对病例进行组织病理学对照。
在通过FNAC诊断的25例患者中，男性18例，女性7例，年龄范围为6至85岁。3例患者接受了超声引导下的FNAC检查，22例患者接受了CT引导下的FNAC检查。在25例病例中，17例为恶性，6例为良性，2例结果不满意。FNAC对83.3%的病例诊断有用。14例病例有活检和/或细胞块对照。在恶性病例中，鳞状细胞癌或腺癌导致的纵隔侵犯最多，17例中有8例（47%）。在非肿瘤性疾病中，非特异性炎症是最常见的原因，占总病例数的2例（8%），其次是结核、神经鞘瘤、胸腺瘤和囊性病变各1例。
超声或CT引导下的FNAC是一种安全、微创且经济有效的检查方法，可对纵隔肿物提供精确诊断，可能无需采用侵入性手术方法。
