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老年患者跌倒与钠-葡萄糖协同转运蛋白2抑制剂——病例报告

Falls and SGLT-2 inhibitors in geriatric patients-A case report.

作者信息

Taşdemir Anil, Belice Tahir, Yüksel Arif

机构信息

Department of Internal Medicine, University of Health Sciences, Bozyaka Training and Research Hospital, Izmir, Turkey.

出版信息

J Family Med Prim Care. 2020 Aug 25;9(8):4454-4455. doi: 10.4103/jfmpc.jfmpc_852_20. eCollection 2020 Aug.

DOI:10.4103/jfmpc.jfmpc_852_20
PMID:33110884
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7586571/
Abstract

With this case report, we want to assess the synergistic effect of both a diuretic and an SGLT-2 inhibitor on the fall event of a patient who is 65 years old and has a history of repeated falls before. After we modified the medications appropriately, she has never experienced a fall event again. So as we know, older adults do not take fall events as a pathological condition instead of a normal physiological aging process. So primary-care physicians should question the fall history of an older patient before starting a drug such as SGLT-2 inhibitors, which is known as an agent that has side effects including falls, dehydration, etc.

摘要

通过本病例报告,我们希望评估利尿剂和SGLT-2抑制剂对一名65岁且既往有反复跌倒史患者跌倒事件的协同作用。在我们适当调整用药后,她再也没有经历过跌倒事件。如我们所知,老年人并不将跌倒事件视为一种病理状况,而是正常的生理衰老过程。因此,基层医疗医生在开始使用如SGLT-2抑制剂这类已知有包括跌倒、脱水等副作用的药物之前,应该询问老年患者的跌倒史。

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本文引用的文献

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Time for a Systems Biological Approach to Cognitive Aging?-A Critical Review.是时候采用系统生物学方法研究认知衰老了吗?——一项批判性综述
Front Aging Neurosci. 2020 May 12;12:114. doi: 10.3389/fnagi.2020.00114. eCollection 2020.
2
Cognitive compensatory mechanisms in normal aging: a study on verbal fluency and the contribution of other cognitive functions.正常衰老中的认知补偿机制:一项关于言语流畅性及其他认知功能贡献的研究
Aging (Albany NY). 2019 Jun 22;11(12):4090-4106. doi: 10.18632/aging.102040.
3
Orthostatic Hypotension and Falls in Older Adults: A Systematic Review and Meta-analysis.老年人直立性低血压与跌倒:系统评价和荟萃分析。
J Am Med Dir Assoc. 2019 May;20(5):589-597.e5. doi: 10.1016/j.jamda.2018.11.003. Epub 2018 Dec 21.
4
Revisit, Subsequent Hospitalization, Recurrent Fall, and Death Within 6 Months After a Fall Among Elderly Emergency Department Patients.老年急诊科患者跌倒后6个月内的复诊、再次住院、反复跌倒及死亡情况
Ann Emerg Med. 2017 Oct;70(4):516-521.e2. doi: 10.1016/j.annemergmed.2017.05.023. Epub 2017 Jul 5.
5
Predictors of mortality in geriatric trauma patients: a systematic review and meta-analysis.老年创伤患者死亡的预测因素:系统评价和荟萃分析。
J Trauma Acute Care Surg. 2014 Mar;76(3):894-901. doi: 10.1097/TA.0b013e3182ab0763.
6
Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome.关于直立性低血压、神经介导性晕厥和姿势性心动过速综合征定义的共识声明。
Clin Auton Res. 2011 Apr;21(2):69-72. doi: 10.1007/s10286-011-0119-5.
7
Activity restriction induced by fear of falling and objective and subjective measures of physical function: a prospective cohort study.因害怕跌倒导致的活动受限以及身体功能的客观和主观测量:一项前瞻性队列研究。
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8
The epidemiology of falls and syncope.跌倒与晕厥的流行病学
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