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骨髓活检中慢性淋巴细胞白血病/小淋巴细胞淋巴瘤与急性髓系白血病共存。

Concurrence of chronic lymphocytic leukaemia/small lymphocytic lymphoma and acute myeloid leukaemia in a bone marrow biopsy.

机构信息

Department of Pathology, "San Filippo Neri" Hospital, Rome, Italy.

出版信息

Pol J Pathol. 2020;71(3):285-287. doi: 10.5114/pjp.2020.99798.

DOI:10.5114/pjp.2020.99798
PMID:33112122
Abstract

The association of small lymphocytic lymphoma/chronic lymphocytic leukaemia (CLL) with different malignancies has been reported in the literature. Also the occurrence of a second haematological disease has been described, more frequently as a secondary event in patients receiving chemotherapeutic agents. We report a case of CLL with concurrent acute myeloid leukaemia in an untreated patient, with emphasis on the need of a detailed immunomorphological study to identify the coexistence of the two diseases in the same pathological tissue.

摘要

文献中报道了小淋巴细胞淋巴瘤/慢性淋巴细胞白血病(CLL)与不同恶性肿瘤的关联。也有描述发生第二种血液系统疾病的情况,在接受化疗药物治疗的患者中更常作为继发事件出现。我们报告了一例未经治疗的 CLL 合并急性髓系白血病患者,重点强调需要进行详细的免疫形态学研究,以确定两种疾病在同一病理组织中的共存。

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