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康复治疗起始时间与高级别胶质瘤患者结局的关系:一项回顾性队列研究。

Time to treatment initiation and outcomes in high-grade glioma patients in rehabilitation: a retrospective cohort study.

机构信息

Department of Surgery, New York Presbyterian-Columbia University Medical Center, New York, NY 10032, USA.

Department of Public Health Sciences, University of Rochester Medical Center, Rochester, NY 14642, USA.

出版信息

CNS Oncol. 2020 Dec 1;9(4):CNS64. doi: 10.2217/cns-2020-0018. Epub 2020 Oct 28.

Abstract

To investigate wait time (WT) for chemoradiation and survival in post-op high-grade glioma (HGG) patients admitted to inpatient rehabilitation compared with those discharged home.  A total of 291 HGG patients (14.4% grade III and 84.9% grade IV) were included in this retrospective cohort study. Patients were grouped by disposition following surgery. Median length of stay was longer in acute inpatient rehabilitation facility (AIRF) patients (10d) compared with patients discharged home (3d). AIRF admission was associated with higher odds of excessive treatment delay. Median survival for AIRF patients less than for patients discharged home (42.9 vs 72.71 weeks). WT was not associated with survival even after adjusting for prognostic factors. HGG patients discharged to rehabilitation facilities have longer length of stay, longer WT and shorter survival compared with patients discharged home.

摘要

本研究旨在探讨与出院回家的患者相比,接受放化疗的术后高级别胶质瘤(HGG)患者在住院康复治疗中的等待时间(WT)和生存情况。该回顾性队列研究共纳入 291 名 HGG 患者(14.4%为 3 级,84.9%为 4 级)。患者根据术后的处置情况进行分组。与出院回家的患者(3 天)相比,急性住院康复机构(AIRF)患者的中位住院时间更长(10 天)。AIRF 入院与过度治疗延迟的几率较高相关。AIRF 患者的中位生存期短于出院回家的患者(42.9 周 vs 72.71 周)。即使在调整了预后因素后,WT 与生存也没有相关性。与出院回家的患者相比,转至康复机构的 HGG 患者的住院时间更长,WT 更长,生存时间更短。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/23be624739f7/cns-09-64-g1.jpg

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