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康复治疗起始时间与高级别胶质瘤患者结局的关系:一项回顾性队列研究。

Time to treatment initiation and outcomes in high-grade glioma patients in rehabilitation: a retrospective cohort study.

机构信息

Department of Surgery, New York Presbyterian-Columbia University Medical Center, New York, NY 10032, USA.

Department of Public Health Sciences, University of Rochester Medical Center, Rochester, NY 14642, USA.

出版信息

CNS Oncol. 2020 Dec 1;9(4):CNS64. doi: 10.2217/cns-2020-0018. Epub 2020 Oct 28.

DOI:10.2217/cns-2020-0018
PMID:33112686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7737197/
Abstract

To investigate wait time (WT) for chemoradiation and survival in post-op high-grade glioma (HGG) patients admitted to inpatient rehabilitation compared with those discharged home.  A total of 291 HGG patients (14.4% grade III and 84.9% grade IV) were included in this retrospective cohort study. Patients were grouped by disposition following surgery. Median length of stay was longer in acute inpatient rehabilitation facility (AIRF) patients (10d) compared with patients discharged home (3d). AIRF admission was associated with higher odds of excessive treatment delay. Median survival for AIRF patients less than for patients discharged home (42.9 vs 72.71 weeks). WT was not associated with survival even after adjusting for prognostic factors. HGG patients discharged to rehabilitation facilities have longer length of stay, longer WT and shorter survival compared with patients discharged home.

摘要

本研究旨在探讨与出院回家的患者相比,接受放化疗的术后高级别胶质瘤(HGG)患者在住院康复治疗中的等待时间(WT)和生存情况。该回顾性队列研究共纳入 291 名 HGG 患者(14.4%为 3 级,84.9%为 4 级)。患者根据术后的处置情况进行分组。与出院回家的患者(3 天)相比,急性住院康复机构(AIRF)患者的中位住院时间更长(10 天)。AIRF 入院与过度治疗延迟的几率较高相关。AIRF 患者的中位生存期短于出院回家的患者(42.9 周 vs 72.71 周)。即使在调整了预后因素后,WT 与生存也没有相关性。与出院回家的患者相比,转至康复机构的 HGG 患者的住院时间更长,WT 更长,生存时间更短。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/3feeb57e7123/cns-09-64-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/23be624739f7/cns-09-64-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/43649b86e825/cns-09-64-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/3feeb57e7123/cns-09-64-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/23be624739f7/cns-09-64-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/43649b86e825/cns-09-64-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a86/7737197/3feeb57e7123/cns-09-64-g3.jpg

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本文引用的文献

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Newly diagnosed glioblastoma: adverse socioeconomic factors correlate with delay in radiotherapy initiation and worse overall survival.新诊断的胶质母细胞瘤:不良社会经济因素与放疗开始延迟及总体生存率较差相关。
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Sci Rep. 2023 Feb 16;13(1):2766. doi: 10.1038/s41598-023-29790-8.
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Post-acute Care Needs and Benefits of Inpatient Rehabilitation Care for the Oncology Patient.肿瘤患者住院康复治疗的后期护理需求和获益。
Curr Oncol Rep. 2023 Mar;25(3):155-162. doi: 10.1007/s11912-023-01366-9. Epub 2023 Feb 2.
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Predictors of functional outcomes in adults with brain tumor undergoing rehabilitation treatment: a systematic review.脑肿瘤康复治疗成人功能结局的预测因素:系统评价。
Eur J Phys Rehabil Med. 2022 Oct;58(5):666-674. doi: 10.23736/S1973-9087.22.07510-4. Epub 2022 Jul 8.
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