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灼口综合征进展中临床因素的心理测量评估

Psychometric Assessment of Clinical Factors in Burning Mouth Syndrome Progression.

作者信息

Garcia-Martinez Ana, Tvarijonaviciute Asta, López-Jornet Pia

机构信息

Department of Dermatology, Stomatology, Radiology and Physical Medicine, Faculty of Medicine, University of Murcia, Hospital Morales Meseguer Clinica Odontologica Marques Velez S/N, Murcia, Spain.

Interdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, Espinardo, Murcia, Spain.

出版信息

Int Dent J. 2025 May 30;75(4):100838. doi: 10.1016/j.identj.2025.100838.

Abstract

OBJECTIVE

This study employed psychometric tools to assess the impact of factors such as age, symptom location, and duration on the improvement in burning mouth syndrome (BMS).

MATERIALS AND METHODS

A total of 86 women with BMS were divided into 4 groups: laser plus clonazepam (n = 24), sham laser placebo (n = 20), laser only (n = 22), and clonazepam only (n = 20). Symptom severity was measured using the Visual Analog Scale (VAS), while depression and anxiety were evaluated using the Hospital Anxiety and Depression Scale (HADS). Stress levels were assessed using the Perceived Stress Scale (PSS) and somnolence with the Epworth Somnolence Scale (ESS). Questionnaires were completed at baseline, 1 month post-treatment, and at 3 months of follow-up.

RESULTS

Symptom intensity significantly decreased from baseline to study end (P < .001), with minor increases during follow-up. Stress levels also significantly declined (P = .016), while anxiety, depression, and somnolence showed no significant changes (P > .05). Symptom intensity correlated with age (P < .001), and initial anxiety correlated with disease duration (P = .027).

CONCLUSION

Age, disease duration, and symptom location did not significantly influence symptom improvement, psychological state, or somnolence. Further multidisciplinary research is needed.

摘要

目的

本研究采用心理测量工具评估年龄、症状部位和病程等因素对灼口综合征(BMS)改善情况的影响。

材料与方法

总共86名患有BMS的女性被分为4组:激光加氯硝西泮组(n = 24)、假激光安慰剂组(n = 20)、单纯激光组(n = 22)和单纯氯硝西泮组(n = 20)。使用视觉模拟量表(VAS)测量症状严重程度,同时使用医院焦虑抑郁量表(HADS)评估抑郁和焦虑情况。使用感知压力量表(PSS)评估压力水平,使用爱泼华嗜睡量表(ESS)评估嗜睡情况。在基线、治疗后1个月和随访3个月时完成问卷调查。

结果

从基线到研究结束,症状强度显著降低(P < .001),随访期间略有增加。压力水平也显著下降(P = .016),而焦虑、抑郁和嗜睡情况无显著变化(P > .05)。症状强度与年龄相关(P < .001),初始焦虑与病程相关(P = .027)。

结论

年龄、病程和症状部位对症状改善、心理状态或嗜睡情况无显著影响。需要进一步开展多学科研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c93c/12166677/5c0af3c6ef7b/gr1.jpg

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