Ramasamy Shobana, Joseph Mini, Jiwanmall Stephen Amarjeet, Kattula Dheeraj, Nandyal Munaf Babajan, Abraham Vijay, Samarasam Inian, Paravathareddy Sandhiya, Paul Thomas V, Rajaratnam Simon, Thomas Nihal, Kapoor Nitin
Weill Cornell Medicine, New York, NY, USA.
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Eur Endocrinol. 2020 Oct;16(2):148-151. doi: 10.17925/EE.2020.16.2.148. Epub 2020 Oct 6.
The global prevalence of obesity is increasing and has nearly doubled in the last decade, disproportionately impacting less-developed countries. The aim of this cross-sectional study was to analyse health-related quality of life (HRQOL) in morbidly obese women attending a bariatric clinic in India, and assess potential obesity indicators that can be utilised in under-resourced settings, to better understand HRQOL of individual patients.
Anthropometric measurements were collected, including waist circumference, hip circumference, waist-hip ratio, waist-height ratio and body mass index (BMI). HRQOL was assessed using an obesity-related quality-of-life questionnaire focused on the impact of obesity on physical distress, self-esteem, sexual life and work life.
The average BMI of study participants was 39.6 kg/m2, with an average HRQOL of 40.2%. The strongest correlation was noted between BMI and HRQOL (R2=0.16). Exploratory analyses demonstrated that patients with higher BMI quartiles had lower scores for physical impact and psychosocial impact, and higher scores for sexual health, comfort with food, and experience with dieting compared to patients in lower quartiles.
In South Indian, middle-aged, morbidly obese women, HRQOL is lower than average and is highly correlated with BMI, with different BMI levels having higher impacts in different subcategories, supporting the need for an individualised therapeutic focus for each patient.
全球肥胖患病率呈上升趋势，在过去十年中几乎翻了一番，对欠发达国家的影响尤为严重。这项横断面研究的目的是分析在印度一家减肥诊所就诊的病态肥胖女性的健康相关生活质量（HRQOL），并评估在资源匮乏地区可利用的潜在肥胖指标，以便更好地了解个体患者的HRQOL。
收集人体测量数据，包括腰围、臀围、腰臀比、腰高比和体重指数（BMI）。使用一份与肥胖相关的生活质量问卷评估HRQOL，该问卷侧重于肥胖对身体不适、自尊、性生活和工作生活的影响。
研究参与者的平均BMI为39.6kg/m²，平均HRQOL为40.2%。BMI与HRQOL之间的相关性最强（R²=0.16）。探索性分析表明，与BMI较低四分位数的患者相比，BMI较高四分位数的患者在身体影响和心理社会影响方面得分较低，而在性健康、对食物的舒适度和节食经历方面得分较高。
在南印度中年病态肥胖女性中，HRQOL低于平均水平，且与BMI高度相关，不同BMI水平在不同亚类中有更高影响，这支持了对每位患者进行个体化治疗的必要性。
