Kalra Sanjay, Kapoor Nitin, Bhattacharya Saptarshi, Aydin Hassan, Coetzee Ankia
Bharti Hospital, Karnal 132001, India.
Christian Medical College Vellore, Vellore 632004, India.
Med Sci (Basel). 2020 Dec 21;8(4):51. doi: 10.3390/medsci8040051.
Obesity has reached pandemic proportions. Hormonal and metabolic imbalances are the key factors that lead to obesity. South Asian populations have a unique phenotype, peculiar dietary practices, and a high prevalence of consanguinity. Moreover, many lower middle-income countries lack appropriate resources, super-specialists, and affordability to manage this complex disorder. Of late, there has been a substantial increase in both obesity and diabesity in India. Thus, many more patients are being managed by different types of bariatric procedures today than ever before. These patients have many types of endocrine and metabolic disturbances before and after bariatric surgery. Therefore, these patients should be managed by experts who have knowledge of both bariatric surgery and endocrinology. The authors propose "Barocrinology", a novel terminology in medical literature, to comprehensively describe the field of obesity medicine highlighting the role of knowing endocrine physiology for understating its evolution, insights into its complications and appreciating the changes in the hormonal milieu following weight loss therapies including bariatric surgery. Barocrinology, coined as a portmanteau of "baro" (weight) and endocrinology, focuses upon the endocrine and metabolic domains of weight physiology and pathology. This review summarizes the key pointers of bariatric management from an endocrine perspective.
肥胖已达到流行程度。激素和代谢失衡是导致肥胖的关键因素。南亚人群具有独特的表型、特殊的饮食习惯以及较高的近亲结婚率。此外,许多中低收入国家缺乏管理这种复杂疾病所需的适当资源、专科医生以及可负担性。近年来,印度的肥胖症和糖尿病肥胖症患者数量都大幅增加。因此,如今接受不同类型减肥手术治疗的患者比以往任何时候都多。这些患者在减肥手术前后存在多种内分泌和代谢紊乱。所以,这些患者应由既了解减肥手术又了解内分泌学的专家来管理。作者提出了“体重内分泌学”这一医学文献中的新术语,以全面描述肥胖医学领域,强调了解内分泌生理学对于理解肥胖症的演变、洞察其并发症以及认识包括减肥手术在内的体重减轻疗法后激素环境变化的作用。“体重内分泌学”由“baro”(体重)和内分泌学合成,专注于体重生理学和病理学的内分泌和代谢领域。本综述从内分泌学角度总结了减肥治疗的关键要点。