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成人糖尿病患者代谢手术术前医学优化的专家意见。

Expert opinion on the preoperative medical optimization of adults with diabetes undergoing metabolic surgery.

作者信息

Bhattacharya Saptarshi, Kalra Sanjay, Kapoor Nitin, Singla Rajiv, Dutta Deep, Aggarwal Sameer, Khandelwal Deepak, Surana Vineet, Dhingra Atul, Kantroo Viny, Chittawar Sachin, Deka Nilakshi, Bindal Vivek, Dutta Puja

机构信息

Endocrinology, Max Superspeciality Hospital, New Delhi 110092, India.

Endocrinology, Bharti Hospital, Karnal 132001, Haryana, India.

出版信息

World J Diabetes. 2021 Oct 15;12(10):1587-1621. doi: 10.4239/wjd.v12.i10.1587.

Abstract

Diabetes mellitus (DM) and obesity are interrelated in a complex manner, and their coexistence predisposes patients to a plethora of medical problems. Metabolic surgery has evolved as a promising therapeutic option for both conditions. It is recommended that patients, particularly those of Asian origin, maintain a lower body mass index threshold in the presence of uncontrolled DM. However, several comorbidities often accompany these chronic diseases and need to be addressed for successful surgical outcome. Laparoscopic Roux-en-Y gastric bypass (RYGB) and laparoscopic sleeve gastrectomy (LSG) are the most commonly used bariatric procedures worldwide. The bariatric benefits of RYGB and LSG are similar, but emerging evidence indicates that RYGB is more effective than LSG in improving glycemic control and induces higher rates of long-term DM remission. Several scoring systems have been formulated that are utilized to predict the chances of remission. A glycemic target of glycated hemoglobin < 7% is a reasonable goal before surgery. Cardiovascular, pulmonary, gastrointestinal, hepatic, renal, endocrine, nutritional, and psychological optimization of surgical candidates improves perioperative and long-term outcomes. Various guidelines for preoperative care of individuals with obesity have been formulated, but very few specifically focus on the concerns arising from the presence of concomitant DM. It is hoped that this statement will lead to the standardization of presurgical management of individuals with DM undergoing metabolic surgery.

摘要

糖尿病(DM)与肥胖以复杂的方式相互关联,它们的共存使患者易患多种医学问题。代谢手术已发展成为针对这两种病症的一种有前景的治疗选择。建议患者,尤其是亚洲裔患者,在糖尿病未得到控制的情况下保持较低的体重指数阈值。然而,这些慢性病常伴有多种合并症,为了手术取得成功结果需要对其进行处理。腹腔镜Roux-en-Y胃旁路术(RYGB)和腹腔镜袖状胃切除术(LSG)是全球最常用的减肥手术。RYGB和LSG的减肥效果相似,但新出现的证据表明,RYGB在改善血糖控制方面比LSG更有效,且能诱导更高的长期糖尿病缓解率。已经制定了几种评分系统来预测缓解的可能性。糖化血红蛋白<7%的血糖目标是手术前的合理目标。对手术候选人进行心血管、肺、胃肠道、肝脏、肾脏、内分泌、营养和心理方面的优化可改善围手术期和长期结果。已经制定了各种肥胖个体术前护理指南,但很少有专门针对合并糖尿病所引发问题的指南。希望本声明将导致接受代谢手术的糖尿病患者术前管理的标准化。

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