Department of Ophthalmology, Ankara City Hospital, Ankara, Turkey.
Department of Ophthalmology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Int Ophthalmol. 2020 Dec;40(12):3357-3362. doi: 10.1007/s10792-020-01523-0. Epub 2020 Oct 28.
To investigate the effect of the diabetes on cataract formation by Pentacam Scheimpflug topography system.
Thirty diabetic patients and thirty-five healthy control subjects were included in the study. Exclusion criteria were smoking, high refractive error, any systemic disease or drug usage associated with cataract formation and to have diabetic retinopathy. The duration of diabetes and HbA1c level were recorded. A comprehensive ophthalmologic examination was performed in all cases. Pentacam (Oculus, Wetzlar, Germany) three-dimensional lens densitometer module was used to measure density of anterior, nuclear and posterior lens regions.
Mean age of group 1 and group 2 was 37.80 ± 5.51 years and 36.51 ± 3.77 years, respectively. There were not any difference between groups in the means of age and sex (P = .271; P = .700). The mean duration of diabetes in group 1 was 4.23 ± 3.71 years (6 months-10 year). The mean HbA1c level was 8.12 ± 2.07% (5.4-12.7%). Anterior, nuclear and posterior mean lens densitometry measurements were significantly higher in group 1 (diabetic group) than group 2 (control group) [(8.90 ± 0.59%; 8.05 ± 0.72% P = < .001), (7.52 ± 0.31%; 7.00 ± 0.59% P = < .001), (7.25 ± 0.31%; 6.90 ± 0.73% P = .006), respectively].
Diabetes may have cataractous effect in anterior, nuclear and posterior regions of the lens.
通过 Pentacam Scheimpflug 体层摄影系统研究糖尿病对白内障形成的影响。
研究纳入 30 名糖尿病患者和 35 名健康对照者。排除标准为吸烟、高度屈光不正、任何与白内障形成相关的系统性疾病或药物使用以及糖尿病视网膜病变。记录糖尿病的持续时间和 HbA1c 水平。所有患者均行全面眼科检查。使用 Pentacam（Oculus，德国威茨拉尔）三维晶状体密度计模块测量前、核和后晶状体区域的密度。
第 1 组和第 2 组的平均年龄分别为 37.80±5.51 岁和 36.51±3.77 岁。两组在年龄和性别方面无差异（P=0.271；P=0.700）。第 1 组糖尿病的平均病程为 4.23±3.71 年（6 个月-10 年）。平均 HbA1c 水平为 8.12±2.07%（5.4-12.7%）。第 1 组（糖尿病组）前、核和后晶状体平均密度测量值明显高于第 2 组（对照组）[（8.90±0.59%；P<0.001），（7.52±0.31%；P<0.001），（7.25±0.31%；P=0.006）]。
糖尿病可能对晶状体前、核和后区有白内障效应。
