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酿酒酵母营养生长所必需的两个新基因的特性分析:核苷酸序列测定及染色体定位

Characterization of two new genes essential for vegetative growth in Saccharomyces cerevisiae: nucleotide sequence determination and chromosome mapping.

作者信息

Dubois E, Bercy J, Descamps F, Messenguy F

机构信息

Institut de Recherches du CERIA, Brussels, Belgium.

出版信息

Gene. 1987;55(2-3):265-75. doi: 10.1016/0378-1119(87)90286-1.

Abstract

Based on nucleotide sequence determination, we have identified two new yeast genes FUN80 and FUN81 located on chromosome XIII. They are both essential for cellular growth but their function is still unknown. FUN80 is closely linked to the ARGRI (or ARG80) gene while FUN81 is located next to the ARGRII (or ARG81) gene. Interestingly, the proteins encoded by these two genes have a long stretch of acidic amino acids within their C-terminal portions.

摘要

基于核苷酸序列测定,我们鉴定出位于第十三号染色体上的两个新的酵母基因FUN80和FUN81。它们对于细胞生长都是必需的,但其功能仍然未知。FUN80与ARGRI(或ARG80)基因紧密连锁,而FUN81位于ARGRII(或ARG81)基因旁边。有趣的是,这两个基因编码的蛋白质在其C末端部分有一段很长的酸性氨基酸序列。

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