• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Some like it hot: Candida activation of inflammasomes.

作者信息

Camilli Giorgio, Griffiths James S, Ho Jemima, Richardson Jonathan P, Naglik Julian R

机构信息

Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.

出版信息

PLoS Pathog. 2020 Oct 29;16(10):e1008975. doi: 10.1371/journal.ppat.1008975. eCollection 2020 Oct.

DOI:10.1371/journal.ppat.1008975
PMID:33119702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7595283/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7595283/67726cfd1311/ppat.1008975.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7595283/67726cfd1311/ppat.1008975.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7595283/67726cfd1311/ppat.1008975.g001.jpg

相似文献

1
Some like it hot: Candida activation of inflammasomes.有人喜欢热辣:念珠菌激活炎性小体。
PLoS Pathog. 2020 Oct 29;16(10):e1008975. doi: 10.1371/journal.ppat.1008975. eCollection 2020 Oct.
2
Editorial: Crystal death: it's not always the inflammasome..社论:晶体性死亡:并非总是炎性小体所致
J Leukoc Biol. 2017 Jul;102(1):1-4. doi: 10.1189/jlb.3CE0117-022R.
3
Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.自身免疫性NZB小鼠中NLRP3和AIM2炎性小体功能缺陷
J Immunol. 2015 Aug 1;195(3):1233-41. doi: 10.4049/jimmunol.1402859. Epub 2015 Jun 26.
4
Inflammasomes and Acute Kidney Injury.炎性小体与急性肾损伤
J Am Soc Nephrol. 2024 Aug 1;35(8):985-987. doi: 10.1681/ASN.0000000000000423. Epub 2024 Jun 14.
5
Inflammasome biology, molecular pathology and therapeutic implications.炎症小体生物学、分子病理学及其治疗意义。
Pharmacol Ther. 2018 Jul;187:133-149. doi: 10.1016/j.pharmthera.2018.02.011. Epub 2018 Feb 18.
6
[Innate immune responses and inflammatory diseases via NLR-inflammasome].通过NLR炎症小体的天然免疫反应与炎症性疾病
Nihon Rinsho. 2012 Nov;70 Suppl 8:242-5.
7
Fyn amplifies NLRP3 inflammasome signaling in Parkinson's disease.Fyn增强帕金森病中的NLRP3炎性小体信号传导。
Aging (Albany NY). 2019 Aug 27;11(16):5871-5873. doi: 10.18632/aging.102210.
8
Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome.NLR 家族富含吡咯烷二硫化物结构域的蛋白 3 炎性小体的翻译后调控。
Front Immunol. 2018 May 18;9:1054. doi: 10.3389/fimmu.2018.01054. eCollection 2018.
9
NEK7: a novel promising therapy target for NLRP3-related inflammatory diseases.NEK7:一种用于NLRP3相关炎症性疾病的新型且有前景的治疗靶点。
Acta Biochim Biophys Sin (Shanghai). 2016 Oct;48(10):966-968. doi: 10.1093/abbs/gmw080. Epub 2016 Aug 25.
10
The Overexpression of Sirtuin1 (SIRT1) Alleviated Lipopolysaccharide (LPS)-Induced Acute Kidney Injury (AKI) via Inhibiting the Activation of Nucleotide-Binding Oligomerization Domain-Like Receptors (NLR) Family Pyrin Domain Containing 3 (NLRP3) Inflammasome.Sirtuin1(SIRT1)的过表达通过抑制核苷酸结合寡聚结构域样受体(NLR)家族含 pyrin 结构域 3(NLRP3)炎性小体的激活缓解脂多糖(LPS)诱导的急性肾损伤(AKI)。
Med Sci Monit. 2019 Apr 13;25:2718-2726. doi: 10.12659/MSM.913146.

引用本文的文献

1
The Interplay between Vaginal Mucosa, Host Immunity and Resident Microbiota in Health and Disease: An Overview and Future Perspectives.阴道黏膜、宿主免疫与常驻微生物群在健康与疾病中的相互作用:综述与未来展望
Microorganisms. 2023 May 5;11(5):1211. doi: 10.3390/microorganisms11051211.
2
Cerebrospinal fluid: a target of some fungi and an overview.脑脊液:一些真菌的靶标及概述。
Mem Inst Oswaldo Cruz. 2023 Mar 20;118:e220251. doi: 10.1590/0074-02760220251. eCollection 2023.
3
Role of Cellular Metabolism during -Host Interactions.细胞代谢在宿主相互作用中的作用。

本文引用的文献

1
Second-Generation Antidiabetic Sulfonylureas Inhibit Candida albicans and Candidalysin-Mediated Activation of the NLRP3 Inflammasome.第二代抗糖尿病磺酰脲类药物抑制白色念珠菌和念珠菌毒素介导的 NLRP3 炎性体激活。
Antimicrob Agents Chemother. 2020 Jan 27;64(2). doi: 10.1128/AAC.01777-19.
2
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor.白念珠菌毒素通过表皮生长因子受体激活先天上皮免疫反应。
Nat Commun. 2019 May 24;10(1):2297. doi: 10.1038/s41467-019-09915-2.
3
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes.
Pathogens. 2022 Jan 28;11(2):184. doi: 10.3390/pathogens11020184.
4
Advances in Antifungal Drug Development: An Up-To-Date Mini Review.抗真菌药物研发进展:最新综述
Pharmaceuticals (Basel). 2021 Dec 16;14(12):1312. doi: 10.3390/ph14121312.
5
Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages.炎性小体介导的 GSDMD 活化促进白色念珠菌从巨噬细胞中逃逸。
Nat Commun. 2021 Nov 18;12(1):6699. doi: 10.1038/s41467-021-27034-9.
6
Identification of Dual-Target Compounds with Antifungal and Anti-NLRP3 Inflammasome Activity.鉴定具有抗真菌和抗 NLRP3 炎性体活性的双重作用靶点化合物。
ACS Infect Dis. 2021 Aug 13;7(8):2522-2535. doi: 10.1021/acsinfecdis.1c00270. Epub 2021 Jul 14.
7
The Known Unknowns of the Immune Response to .对……免疫反应中已知的未知因素 。 你提供的原文似乎不完整,后面缺少具体内容。
J Fungi (Basel). 2021 May 11;7(5):377. doi: 10.3390/jof7050377.
8
Role for IL-1 Family Cytokines in Fungal Infections.白细胞介素-1家族细胞因子在真菌感染中的作用。
Front Microbiol. 2021 Feb 10;12:633047. doi: 10.3389/fmicb.2021.633047. eCollection 2021.
真菌肽毒素 Candidaysin 激活 NLRP3 炎症小体并导致单核吞噬细胞细胞溶解。
Nat Commun. 2018 Oct 15;9(1):4260. doi: 10.1038/s41467-018-06607-1.
4
SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.SYK-CARD9 信号轴促进肠道真菌介导体炎性小体激活,以限制结肠炎和结肠癌。
Immunity. 2018 Sep 18;49(3):515-530.e5. doi: 10.1016/j.immuni.2018.08.024.
5
High-Throughput Screening Identifies Genes Required for Induction of Macrophage Pyroptosis.高通量筛选鉴定诱导巨噬细胞细胞焦亡所需的基因。
mBio. 2018 Aug 21;9(4):e01581-18. doi: 10.1128/mBio.01581-18.
6
A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis.在丝状酿酒酵母背景下进行的全基因组缺失突变体筛选确定麦角固醇是巨噬细胞细胞焦亡的直接触发因子。
mBio. 2018 Jul 31;9(4):e01204-18. doi: 10.1128/mBio.01204-18.
7
Targeting the NLRP3 inflammasome in inflammatory diseases.针对炎症性疾病中的NLRP3炎性小体
Nat Rev Drug Discov. 2018 Aug;17(8):588-606. doi: 10.1038/nrd.2018.97. Epub 2018 Jul 20.
8
Fungal infections in patients with inflammatory bowel disease: A systematic review.炎症性肠病患者的真菌感染:系统评价。
Mycoses. 2018 Jun;61(6):366-376. doi: 10.1111/myc.12753. Epub 2018 Mar 25.
9
NLRP3 inflammasome is a key player in human vulvovaginal disease caused by Candida albicans.NLRP3 炎性小体是白念珠菌引起的人类外阴阴道疾病的关键因素。
Sci Rep. 2017 Dec 19;7(1):17877. doi: 10.1038/s41598-017-17649-8.
10
EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.EphA2 是一种上皮细胞模式识别受体,可识别真菌β-葡聚糖。
Nat Microbiol. 2018 Jan;3(1):53-61. doi: 10.1038/s41564-017-0059-5. Epub 2017 Nov 13.