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工作暴露与肺炎和流感住院相关风险:一项全国性研究。

Work exposure and associated risk of hospitalisation with pneumonia and influenza: A nationwide study.

机构信息

The Heart Centre, Rigshospitalet, Denmark.

Department of Clinical Epidemiology and Department of Cardiology, University of Aalborg, Denmark.

出版信息

Scand J Public Health. 2021 Feb;49(1):57-63. doi: 10.1177/1403494820964974. Epub 2020 Oct 30.

Abstract

BACKGROUND

Pneumonia and influenza are major health concerns and constitute a high economic burden. However, few data are available on the associated risk of pneumonia and influenza and work exposure on a large population scale.

AIM

This study aimed to examine the associated risk of pneumonia and influenza by type of work exposure.

METHODS

By cross-linking administrative Danish registries, we classified people in 10 different profession types. The main outcome was hospitalisation with pneumonia or influenza. A multivariable Poisson regression analysis was used to assess the associated incidence rate ratio (IRR) of being hospitalised with pneumonia or influenza by type of profession.

RESULTS

A total of 1,327,606 people added risk time to the analyses. In a multivariable model, work in day care, public transportation, sewers and nursing home care was associated with an increased risk of hospitalisation with pneumonia compared to work within public administration: IRR=1.20 (95% confidence interval (CI) 1.12-1.28), IRR=1.21 (95% CI 1.09-1.34), IRR=1.61 (95% CI 1.19-2.19) and IRR=1.10 (95% CI 1.03-1.18), respectively. In a multivariable analysis, people working within public transportation were associated with an increased risk of hospitalisation with influenza compared to people working within public administration: IRR=2.54 (95% CI 1.79-3.58).

CONCLUSIONS

摘要

背景

肺炎和流感是主要的健康问题,构成了巨大的经济负担。然而,关于肺炎和流感的相关风险以及工作暴露在大规模人群中的情况,数据有限。

目的

本研究旨在研究不同工作暴露类型与肺炎和流感相关的风险。

方法

通过交叉链接丹麦行政登记处,我们将人群分为 10 种不同职业类型。主要结局是因肺炎或流感住院。采用多变量泊松回归分析评估不同职业类型与肺炎或流感住院相关的发病率比(IRR)。

结果

共有 1327606 人将风险时间加入分析。在多变量模型中,与公共行政部门相比,日托、公共交通、污水和养老院护理工作与肺炎住院风险增加相关:IRR=1.20(95%置信区间(CI)1.12-1.28),IRR=1.21(95% CI 1.09-1.34),IRR=1.61(95% CI 1.19-2.19)和 IRR=1.10(95% CI 1.03-1.18)。在多变量分析中,与公共行政部门相比,从事公共交通工作的人因流感住院的风险增加:IRR=2.54(95% CI 1.79-3.58)。

结论

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b7d/7859585/b5bb5f8ff9e2/10.1177_1403494820964974-fig1.jpg

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