Hall W D
Division of Hypertension, Emory University School of Medicine, Atlanta, GA 30303.
J Clin Hypertens. 1987 Sep;3(3 Suppl):108S-113S.
In summary, hypertensive blacks have an increased overall benefit of therapy in mild hypertension. They also exhibit an accentuated (supersensitive) response to monotherapy with diuretics or calcium channel blockers. They have a blunted response to most beta blocker monotherapy in usual doses, with the possible exceptions of labetalol and pindolol. They also have a blunted response to converting enzyme inhibitor monotherapy, but both beta blocker and converting enzyme responses are equal when diuretic is added.
总之，高血压黑人患者在轻度高血压治疗中总体获益增加。他们对利尿剂或钙通道阻滞剂单药治疗表现出增强的（超敏的）反应。他们对常规剂量的大多数β受体阻滞剂单药治疗反应减弱，拉贝洛尔和吲哚洛尔可能除外。他们对转换酶抑制剂单药治疗反应也减弱，但添加利尿剂时，β受体阻滞剂和转换酶抑制剂的反应相同。
