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使用粉末混合电火花加工对Ti6Al4V ELI进行骨整合的表面改性。

Surface modification for osseointegration of Ti6Al4V ELI using powder mixed sinking EDM.

作者信息

Mughal Mohammad Pervez, Farooq Muhammad Umar, Mumtaz Jabir, Mia Mozammel, Shareef Madiha, Javed Mahnoor, Jamil Muhammad, Pruncu Catalin I

机构信息

Department of Industrial and Manufacturing Engineering, University of Engineering and Technology, Lahore, Pakistan.

Department of Industrial and Manufacturing Engineering, University of Engineering and Technology, Lahore, Pakistan; Department of Industrial and Systems Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea.

出版信息

J Mech Behav Biomed Mater. 2021 Jan;113:104145. doi: 10.1016/j.jmbbm.2020.104145. Epub 2020 Oct 17.

DOI:10.1016/j.jmbbm.2020.104145
PMID:33125953
Abstract

Biomedical implant rejection due to micromotion and inflammation around an implant leads to osteolysis and eventually has an implant failure because of poor osseointegration. To enhance osseointegration, the implant surface modification both at the nano and micro-scale levels is preferred to result in an enhanced interface between the body tissue and implant. The present study focuses on the modification of the surface of Titanium (α+β) ELI medical grade alloy using powder-mixed electric discharge machining (PMEDM). Pulse current, on/off time, and various silicon carbide (SiC) powder concentrations are used as input parameters to comprehend desired surface modifications. Powder concentration is considered as the most important factor to control surface roughness and recast layer depth. A significant decrease in surface fracture density and roughness is observed using a 20 g/l concentration of SiC particles. Elemental mapping analysis has confirmed the migration of Si and the generation of promising surface texture and chemistry. Oxides and carbides enriched surface improved the microhardness of the re-solidified layer from 320 HV to 727 HV. Surface topology reveals nano-porosity (50-200 nm) which enhances osseointegration due to the absorption of proteins especially collagen to the surface.

摘要

由于植入物周围的微动和炎症导致的生物医学植入物排斥会引发骨溶解,最终因骨整合不良而导致植入失败。为了增强骨整合,在纳米和微米尺度上对植入物表面进行改性是首选,以在身体组织和植入物之间形成增强的界面。本研究重点关注使用粉末混合电火花加工(PMEDM)对钛(α+β)ELI医用级合金表面进行改性。脉冲电流、通断时间和各种碳化硅(SiC)粉末浓度用作输入参数,以了解所需的表面改性。粉末浓度被认为是控制表面粗糙度和重铸层深度的最重要因素。使用20 g/l浓度的SiC颗粒时,观察到表面裂纹密度和粗糙度显著降低。元素映射分析证实了Si的迁移以及有前景的表面纹理和化学成分的生成。富含氧化物和碳化物的表面将再凝固层的显微硬度从320 HV提高到727 HV。表面拓扑结构显示出纳米孔隙率(50-200 nm),由于蛋白质尤其是胶原蛋白在表面的吸附,这增强了骨整合。

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