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西澳成年人 DXA 参考值和人体测量学筛查内脏肥胖。

DXA reference values and anthropometric screening for visceral obesity in Western Australian adults.

机构信息

School of Human Sciences M408 (Exercise and Sport Science), The University of Western Australia, 35 Stirling Hwy, Crawley, WA, 6009, Australia.

Body Composition Technologies, Pty Ltd, South Perth, WA, Australia.

出版信息

Sci Rep. 2020 Oct 30;10(1):18731. doi: 10.1038/s41598-020-73631-x.

DOI:10.1038/s41598-020-73631-x
PMID:33127940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7599223/
Abstract

Limited reference values exist for visceral adipose tissue (VAT) mass measured by DXA. The objectives of this study were to provide reference values for DXA-derived VAT mass and compare the association with anthropometry measures. The study cohort comprised 677 men and 738 women aged 18-65 years from Western Australia. Whole-body scans using a GE Lunar iDXA and anthropometry measures were collected. Reference percentile data were stratified by sex and age. Correlation analysis compared DXA-derived and anthropometry variables. Specificity, sensitivity, and Youden's Index were used to evaluate the ability of anthropometric thresholds to predict individuals with high VAT. In men, waist circumference (WC), waist-hip ratio, and waist-height ratio (WHtR) had 'high' correlations with VAT mass. In women, only WHtR was 'highly' correlated with VAT mass. Overweight thresholds for WC, along with a body mass index of 25.0 kg/m in women, had the highest combination of sensitivity and specificity when using anthropometry measures to identify individuals with high VAT mass. We provide the first reference data sets for DXA-derived VAT mass among Western Australians. Excessive VAT mass may be identified in men using the overweight WC threshold and in women using both the overweight BMI and WC thresholds.

摘要

通过 DXA 测量内脏脂肪组织 (VAT) 质量的参考值有限。本研究的目的是提供 DXA 衍生的 VAT 质量的参考值,并比较其与人体测量学指标的相关性。研究队列包括来自西澳大利亚的 677 名男性和 738 名年龄在 18-65 岁的女性。使用通用电气 Lunar iDXA 进行全身扫描并测量人体测量学指标。根据性别和年龄对参考百分位数数据进行分层。相关性分析比较了 DXA 衍生变量和人体测量学变量。使用特异性、敏感性和 Youden 指数来评估人体测量学阈值预测高 VAT 个体的能力。在男性中,腰围 (WC)、腰臀比和腰高比 (WHtR) 与 VAT 质量具有“高”相关性。在女性中,只有 WHtR 与 VAT 质量具有“高度”相关性。使用人体测量学指标识别高 VAT 质量个体时,WC 的超重阈值以及女性的 BMI 为 25.0kg/m2 时,具有最高的敏感性和特异性组合。我们提供了澳大利亚西部 DXA 衍生 VAT 质量的第一批参考数据集。男性可能使用超重 WC 阈值,女性可能同时使用超重 BMI 和 WC 阈值来识别过多的 VAT 质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/ff8ff3b8ec35/41598_2020_73631_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/2b4c02ce4f21/41598_2020_73631_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/053ab6e219ac/41598_2020_73631_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/83547f940539/41598_2020_73631_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/ff8ff3b8ec35/41598_2020_73631_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/2b4c02ce4f21/41598_2020_73631_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/053ab6e219ac/41598_2020_73631_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/83547f940539/41598_2020_73631_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ae3/7599223/ff8ff3b8ec35/41598_2020_73631_Fig4_HTML.jpg

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