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2019冠状病毒病与肥胖症:减重手术具有保护作用吗?对意大利(伦巴第大区)一家大型中心2145例接受减重代谢手术患者的回顾性分析

COVID-19 and Obesity: Is Bariatric Surgery Protective? Retrospective Analysis on 2145 Patients Undergone Bariatric-Metabolic Surgery from High Volume Center in Italy (Lombardy).

作者信息

Uccelli Matteo, Cesana Giovanni Carlo, De Carli Stefano Maria, Ciccarese Francesca, Oldani Alberto, Zanoni Adelinda Angela Giulia, Giorgi Riccardo, Villa Roberta, Ismail Ayman, Targa Simone, D'Alessio Andrea, Cesana Giancarlo, Mantovani Lorenzo, Olmi Stefano

机构信息

General and Oncologic Surgery Department - Centre of Bariatric Surgery, San Marco Hospital GSD, Corso Europa, 7, 24040, Zingonia, BG, Italy.

Internal Medicine and COVID Medical Department, San Marco Hospital GSD, Zingonia, BG, Italy.

出版信息

Obes Surg. 2021 Mar;31(3):942-948. doi: 10.1007/s11695-020-05085-z. Epub 2020 Oct 31.

DOI:10.1007/s11695-020-05085-z
PMID:33128218
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7599117/
Abstract

INTRODUCTION

On February 20, 2020, a severe case of pneumonia due to SARS-CoV-2 was diagnosed in northern Italy (Lombardy). Some studies have identified obesity as a risk factor for severe disease in patients with COVID-19. The purpose of this study was to investigate the incidence of SARS-CoV-2 infection and its severity in patients who have undergone bariatric surgery.

MATERIAL AND METHODS

During the lockdown period (until May 2020), we contacted operated patients by phone and social networks (e.g., Facebook) to maintain constant contact with them; in addition, we gave the patients a dedicated phone number at which to call us for emergencies. We produced telemedicine and educational videos for obese and bariatric patients, and we submitted a questionnaire to patients who had undergone bariatric surgery in the past.

RESULTS

A total of 2145 patients (313 male; 1832 female) replied to the questionnaire. Mean presurgical BMI: 44.5 ± 6.8 kg/m. Mean age: 44.0 ± 10.0 year. Mean BMI after surgery: 29.3 ± 5.5 kg/m (p < 0.05). From February to May 2020, 8.4% of patients reported that they suffered from at least one symptom among those identified as related to SARS-CoV-2 infection. Thirteen patients (0.6%) tested positive for COVID-19. Six patients (0.3%) were admitted to the COVID Department, and 2 patients (0.1%) were admitted to the ICU.

CONCLUSIONS

Although the reported rates of symptoms and fever were high, only 0.6% of patients tested positive for COVID-19. Among more than 2000 patients who underwent bariatric surgery analyzed in this study, only 0.1% needed ICU admission.

摘要

引言

2020年2月20日,意大利北部(伦巴第大区)确诊了一例由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的肺炎重症病例。一些研究已将肥胖确定为新型冠状病毒肺炎(COVID-19)患者发生重症疾病的一个危险因素。本研究的目的是调查接受过减肥手术的患者中SARS-CoV-2感染的发生率及其严重程度。

材料与方法

在封锁期间(直至2020年5月),我们通过电话和社交网络(如脸书)与接受过手术的患者取得联系,以便与他们保持持续沟通;此外,我们还为患者提供了一个专用电话号码,以便他们在紧急情况下能联系到我们。我们为肥胖和接受过减肥手术的患者制作了远程医疗和教育视频,并向过去接受过减肥手术的患者发放了一份问卷。

结果

共有2145名患者(313名男性;1832名女性)回复了问卷。术前平均体重指数(BMI):44.5±6.8kg/m²。平均年龄:44.0±10.0岁。术后平均BMI:29.3±5.5kg/m²(p<0.05)。2020年2月至5月,8.4%的患者报告称他们出现了至少一种被确定为与SARS-CoV-2感染相关的症状。13名患者(0.6%)新型冠状病毒检测呈阳性。6名患者(0.3%)被收治入新冠科室,2名患者(0.1%)被收治入重症监护病房(ICU)。

结论

尽管报告的症状和发热发生率较高,但只有0.6%的患者新型冠状病毒检测呈阳性。在本研究分析的2000多名接受过减肥手术的患者中,只有0.1%的患者需要入住ICU。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc96/7599117/93440943700d/11695_2020_5085_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc96/7599117/93440943700d/11695_2020_5085_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc96/7599117/93440943700d/11695_2020_5085_Fig1_HTML.jpg

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