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颈椎硬膜外脓肿

Cervical epidural abscess.

作者信息

Lasker B R, Harter D H

机构信息

Department of Neurology, Northwestern University Medical School, Chicago, IL.

出版信息

Neurology. 1987 Nov;37(11):1747-53. doi: 10.1212/wnl.37.11.1747.

Abstract

We present 3 new cases of cervical epidural abscess (CEA), a rare condition, along with a review of 12 other case reports. The average patient age was 45 years; just over half were male. The abscesses usually involved the mid to lower cervical region and extended an average of three to four segments. Neck stiffness was present in all patients; root pain and paresthesias were present less often. Weakness of one to four extremities developed in all but one patient. Sensory levels were frequently present, sometimes below the site of the lesion. All but two patients were febrile. All but two had elevated CSF protein, and all but two had a pleocytosis; myelography always revealed a complete or partial block. Staphylococcus aureus was the causative organism in 8 of 11 patients. CEA should be considered in a patient with neck stiffness, paresthesias, and/or radicular pain so that CT or myelography followed by surgical decompression and/or antimicrobial drugs can be initiated before prolonged weakness develops. One of our patients developed a syrinx causing a new neurologic deficit 3 years after treatment. Delayed syringomyelia, a rare complication of extramedullary lesions, lends support to vascular occlusion as the major mechanism of damage in epidural abscess.

摘要

我们报告了3例罕见的颈椎硬膜外脓肿(CEA)新病例,并对其他12例病例报告进行了回顾。患者平均年龄为45岁;男性略多于半数。脓肿通常累及颈椎中下段,平均延伸三到四个节段。所有患者均有颈部僵硬;根性疼痛和感觉异常较少见。除1例患者外,所有患者均出现一至四肢无力。感觉平面常见,有时低于病变部位。除2例患者外,所有患者均发热。除2例患者外,所有患者脑脊液蛋白均升高,除2例患者外,所有患者均有细胞增多;脊髓造影总是显示完全或部分梗阻。11例患者中有8例的致病菌为金黄色葡萄球菌。对于有颈部僵硬、感觉异常和/或神经根性疼痛的患者,应考虑CEA,以便在出现长期无力之前启动CT或脊髓造影,随后进行手术减压和/或使用抗菌药物。我们的1例患者在治疗3年后出现脊髓空洞症,导致新的神经功能缺损。迟发性脊髓空洞症是髓外病变的一种罕见并发症,支持血管闭塞是硬膜外脓肿损伤的主要机制。

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