Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
Nat Prod Res. 2022 Apr;36(8):2021-2027. doi: 10.1080/14786419.2020.1841189. Epub 2020 Nov 2.
Two new compounds ( and ), belonging to C-20 oxygenated -kauranes-type diterpenoids, were identified from the aerial parts of . Their structures were elucidated by extensive analysis of HRESI-MS and NMR spectroscopic data. Both these two compounds possess a common 7,20-epoxy--kauranes skeleton with a hydroxyl group rarely occurring at C-13. Compounds and were evaluated for their cytotoxic activity against Hela-60 and HepG2 as well as the antibacterial activity against , and
从 中分离得到两个新的化合物（和），属于 C-20 含氧 -贝壳杉烷型二萜类化合物。通过对 HRESI-MS 和 NMR 谱数据的综合分析，确定了它们的结构。这两个化合物都具有一个共同的 7,20-环氧--贝壳杉烷骨架，在 C-13 位上很少出现羟基。对化合物和对 Hela-60 和 HepG2 的细胞毒性活性以及对 、 和的抗菌活性进行了评价。
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