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(爬行动物:巨蜥科)消化道内分泌细胞的免疫组织化学研究

An immunohistochemical study of endocrine cells in the digestive tract of (Reptile: Varanidae).

作者信息

Mahfud Mahfud, Ernawati Ernawati, Mahmud Nur R Adawiyah, Budipitojo Teguh, Wijayanto Hery

机构信息

Department of Biology Education, University of Muhammadiyah Kupang, East of Nusa Tenggara Province, Indonesia.

Department of Veterinary Anatomy, Faculty of Veterinary Medicine, Gajah Mada University, Yogyakarta, Indonesia.

出版信息

Vet World. 2020 Sep;13(9):1737-1742. doi: 10.14202/vetworld.2020.1737-1742. Epub 2020 Sep 1.

DOI:10.14202/vetworld.2020.1737-1742
PMID:33132583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7566259/
Abstract

AIM

The aim of the study was to identify the distribution pattern and frequency of endocrine cell types in the digestive tract of .

MATERIALS AND METHODS

The presence of endocrine cells (glucagon, somatostatin, and serotonin) in the digestive tract (esophagus, stomach, and intestine) was detected using the avidin-biotin complex (ABC) method.

RESULTS

Three types of endocrine cells immunoreactive to antisera glucagon, serotonin, and somatostatin were found in the caudal portion of the small and large intestines but were not observed in the esophagus, stomach, and caput and medial sections of the small intestine. Endocrine cells distributed in the digestive tract of vary in color intensity, from weak to sharp, in response to the primer antibody.

CONCLUSION

Endocrine cells in the digestive tract that is immunoreactive to glucagon, somatostatin, and serotonin are those found in the caudal portion of the small and large intestines. They are varied in distribution pattern, frequency, and color intensity.

摘要

目的

本研究的目的是确定[具体对象]消化道内分泌细胞类型的分布模式和频率。

材料与方法

采用抗生物素蛋白-生物素复合物(ABC)法检测消化道(食管、胃和肠)中内分泌细胞(胰高血糖素、生长抑素和5-羟色胺)的存在情况。

结果

在小肠和大肠尾部发现了三种对胰高血糖素、5-羟色胺和生长抑素抗血清呈免疫反应的内分泌细胞,但在食管、胃以及小肠头部和中部未观察到。[具体对象]消化道中分布的内分泌细胞,根据一抗的不同,颜色强度从弱到强不等。

结论

对胰高血糖素、生长抑素和5-羟色胺呈免疫反应的消化道内分泌细胞存在于小肠和大肠尾部。它们在分布模式、频率和颜色强度上各不相同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/087b5f38f35a/Vetworld-13-1737-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/c0316c6ba766/Vetworld-13-1737-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/0cb431941237/Vetworld-13-1737-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/e9dc8ccc4405/Vetworld-13-1737-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/087b5f38f35a/Vetworld-13-1737-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/c0316c6ba766/Vetworld-13-1737-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/0cb431941237/Vetworld-13-1737-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/e9dc8ccc4405/Vetworld-13-1737-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d1/7566259/087b5f38f35a/Vetworld-13-1737-g004.jpg

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本文引用的文献

1
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2
A Pilot Study Investigating the Influence of Glucagon-Like Peptide-1 Receptor Single Nucleotide Polymorphisms on Gastric Emptying Rate in Caucasian Men.一项关于胰高血糖素样肽-1受体单核苷酸多态性对白人男性胃排空率影响的初步研究。
Front Physiol. 2018 Sep 25;9:1331. doi: 10.3389/fphys.2018.01331. eCollection 2018.
3
International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature.
国际基础和临床药理学联合会。生长抑素受体:结构、功能、配体和新命名。
Pharmacol Rev. 2018 Oct;70(4):763-835. doi: 10.1124/pr.117.015388.
4
Extrapancreatic glucagon: Present status.胰外胰高血糖素:现状。
Diabetes Res Clin Pract. 2019 Jan;147:19-28. doi: 10.1016/j.diabres.2018.06.013. Epub 2018 Jun 23.
5
The Diverse Metabolic Roles of Peripheral Serotonin.外周血清素的多种代谢作用
Endocrinology. 2017 May 1;158(5):1049-1063. doi: 10.1210/en.2016-1839.
6
Regional differences in nutrient-induced secretion of gut serotonin.营养物质诱导肠道5-羟色胺分泌的区域差异。
Physiol Rep. 2017 Mar;5(6). doi: 10.14814/phy2.13199.
7
The nutrient-sensing repertoires of mouse enterochromaffin cells differ between duodenum and colon.小鼠十二指肠和结肠的肠嗜铬细胞的营养感知机制有所不同。
Neurogastroenterol Motil. 2017 Jun;29(6). doi: 10.1111/nmo.13046. Epub 2017 Mar 2.
8
The types of endocrine cells in the pancreas of Sunda porcupine (Hystrix javanica).苏门答腊豪猪(马来豪猪)胰腺内分泌细胞的类型。
Vet World. 2016 Jun;9(6):563-7. doi: 10.14202/vetworld.2016.563-567. Epub 2016 Jun 6.
9
Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability.分泌血清素的肠内分泌细胞通过多种机制对葡萄糖可利用性的急性和慢性变化作出反应。
Nutr Metab (Lond). 2015 Dec 15;12:55. doi: 10.1186/s12986-015-0051-0. eCollection 2015.
10
Intestinal GLP-1 and satiation: from man to rodents and back.肠降血糖素(GLP-1)与饱腹感:从人类到啮齿类动物,再回到人类。
Int J Obes (Lond). 2016 Feb;40(2):198-205. doi: 10.1038/ijo.2015.172. Epub 2015 Aug 28.