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从黑暗走向光明:理解慢性病与冠状病毒:一种综合视角

Leading From Darkness to Light: Understanding Chronic Disease and Coronavirus: An Integrative Perspective.

作者信息

Muthukrishnan Prashanth Thalanayar, Vishwanathan Swati

机构信息

Attending Physician, Assistant Professor, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York.

Fellow in Medical Oncology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, New York.

出版信息

Integr Med (Encinitas). 2020 Aug;19(4):8-12.

PMID:33132779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7572137/
Abstract

Disease is defined as complex interaction of 3 things: disease-causing agent, host and environment. The government, CDC and hospital administrations have had reasonable success with the effects of social distancing and coronavirus testing; kudos to them. That addresses 1 of the 3 main factors of a disease; i.e. disease -causing agent. However, there are 2 other ingredients in the complex of a disease; i.e. the host of the disease and finally the environment of the disease. We are the hosts and it is time we take ownership of this ourselves and join the effort with the government towards understanding the dysregulated immune response seen in severe covid-19 and enable the public in strengthening the inner environment and the host immune response. Social distancing can be complete only when the host is prepared to fight the war in the coming fall and winter seasons. The outer environment seems to spontaneously recharging itself as a consequence of social distancing.

摘要

疾病被定义为致病因子、宿主和环境这三者之间的复杂相互作用。政府、疾病控制与预防中心(CDC)以及医院管理部门在社交距离措施和新冠病毒检测方面取得了一定成效;向他们致敬。这解决了疾病三个主要因素中的一个,即致病因子。然而,疾病复合体中还有另外两个要素,即疾病的宿主以及疾病的环境。我们就是宿主,现在是我们自己承担起责任的时候了,我们要与政府共同努力,去了解在重症新冠-19中出现的免疫反应失调情况,并让公众增强内部环境和宿主免疫反应。只有当宿主准备好在即将到来的秋冬季节抗击疫情时,社交距离措施才能彻底落实。由于社交距离措施,外部环境似乎在自行恢复。

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Natl Vital Stat Rep. 2019 Jun;68(6):1-77.
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COVID-19 Does Not Lead to a "Typical" Acute Respiratory Distress Syndrome.新冠病毒肺炎不会导致“典型的”急性呼吸窘迫综合征。
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Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma.5 例危重症 COVID-19 患者接受恢复期血浆治疗。
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Incidence of Bloodstream Infections, Length of Hospital Stay, and Survival in Patients With Recurrent Clostridioides difficile Infection Treated With Fecal Microbiota Transplantation or Antibiotics: A Prospective Cohort Study.复发性艰难梭菌感染患者接受粪便微生物群移植或抗生素治疗后的血流感染发生率、住院时间和生存率:一项前瞻性队列研究。
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Yale J Biol Med. 2018 Jun 28;91(2):177-184. eCollection 2018 Jun.
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