消退型家族性视网膜母细胞瘤患者的中心性浆液性脉络膜视网膜病变

Central Serous Chorioretinopathy in a Case of Regressed Familial Retinoblastoma.

作者信息

Karimi Saeed, Arabi Amir, Shahraki Toktam, Safi Sare

机构信息

Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Ophthalmology, Torfeh Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Ophthalmic Vis Res. 2020 Oct 25;15(4):559-564. doi: 10.18502/jovr.v15i4.7802. eCollection 2020 Oct-Dec.

DOI:10.18502/jovr.v15i4.7802

PMID:33133447

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7591842/

Abstract

PURPOSE

To present a case of central serous chorioretinopathy (CSC) in association with regressed familial retinoblastoma.

CASE REPORT

A 23-year-old man with regressed unilateral familial retinoblastoma in his left eye presented with decreased vision of the left eye since two months ago. The patient had undergone chemotherapy and cryotherapy for the treatment of retinoblastoma 20 years ago. In the left eye, funduscopy disclosed regressed mass of retinoblastoma, inferonasal to the optic disc, and focal subfoveal neurosensory detachment. Optical coherence tomography (OCT) and fluorescein angiography revealed CSC. As there was no sign of recurrence of retinoblastoma and retinal findings did not show late-onset chemotherapy-related retinopathy, the patient was diagnosed with CSC and followed up. After two months, visual acuity of the left eye improved, and repeated macular OCT revealed absorption of the subretinal fluid.

CONCLUSION

Subretinal fluid accumulation in a patient with regressed retinoblastoma is not always a sign of tumor recurrence or a treatment-related retinopathy.

摘要

目的

报告一例与消退性家族性视网膜母细胞瘤相关的中心性浆液性脉络膜视网膜病变（CSC）病例。

病例报告

一名23岁男性，左眼有消退性单侧家族性视网膜母细胞瘤，自两个月前起左眼视力下降。该患者20年前曾接受化疗和冷冻疗法治疗视网膜母细胞瘤。左眼眼底检查发现视网膜母细胞瘤肿块消退，位于视盘鼻下，并有局灶性黄斑下神经感觉脱离。光学相干断层扫描（OCT）和荧光素血管造影显示为CSC。由于没有视网膜母细胞瘤复发的迹象，且视网膜检查未显示迟发性化疗相关视网膜病变，该患者被诊断为CSC并进行随访。两个月后，左眼视力提高，重复进行的黄斑OCT显示视网膜下液吸收。