一名患有回肠末端巨大平滑肌瘤男性患者的肿瘤学罕见病例。
An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum.
作者信息
Zainudin Syaza, Rajanthran Saravana Kumar, Azizan Nornazirah, Hayati Firdaus, Ginawoi Joriana, Suhaimi Khairunnisa Aini, Voo Wan Yee Lilian, Kiram Mohd Fazri, Md Jaki Muhammad Izzuddin, Abd Aziz Siti Haja, Nacathiran Subashini Thevi Nach
机构信息
Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.
Department of Surgery, Queen Elizabeth Hospital, Ministry of Health Malaysia, Kota Kinabalu, Sabah, Malaysia.
出版信息
Oxf Med Case Reports. 2020 Oct 23;2020(10):omaa086. doi: 10.1093/omcr/omaa086. eCollection 2020 Oct.
Leiomyoma is a smooth muscle tumour that can arise in any part of the body especially the uterus. Even though it is traditionally linked with hormonal influence, it can also develop in extrauterine organs with a slight female predominance. It is indistinguishable with gastrointestinal stromal tumour (GIST) histologically. We report a case of a 30-year-old gentleman who presented with a huge painful mass in the right iliac fossa. Computed tomography revealed a 10 × 10 cm homogeneous mass arising from the terminal ileum; he subsequently underwent an open right hemicolectomy. Histology showed a well-circumscribed lesion composed of interlacing bundles of smooth muscle fibres of the submucosa with positive smooth muscle actin and H-Caldesmon stains but negative for DOG-1 and CD117 (c-kit) stains which were consistent with leiomyoma. Despite its rarity, this hormone-related tumour needs to be considered regardless of gender. Immunohistochemistry is paramount as it is histologically identical to GIST.
平滑肌瘤是一种可发生于身体任何部位，尤其是子宫的平滑肌肿瘤。尽管传统上认为它与激素影响有关，但它也可在宫外器官发生，女性略占优势。在组织学上，它与胃肠道间质瘤（GIST）难以区分。我们报告一例30岁男性患者，其右髂窝出现巨大疼痛性肿块。计算机断层扫描显示一个10×10 cm的均匀肿块起源于回肠末端；随后他接受了开放性右半结肠切除术。组织学显示一个边界清楚的病变，由黏膜下层交织的平滑肌纤维束组成，平滑肌肌动蛋白和H - 钙调蛋白染色呈阳性，但DOG - 1和CD117（c - kit）染色呈阴性，这与平滑肌瘤一致。尽管这种肿瘤罕见，但无论性别都需要考虑。免疫组织化学至关重要，因为它在组织学上与GIST相同。
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