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局部自体干细胞在肩袖修复中的应用:“LASCA”技术。

Local Autologous Stem Cells Application in Rotator Cuff Repairs: "LASCA" Technique.

作者信息

Dei Giudici Luca, Castricini Roberto

机构信息

Orthopedic Unit, Casa di Cura "Villa Igea" Hospital, Ancona (AN), Italy.

出版信息

Arthrosc Tech. 2020 Oct 16;9(10):e1571-e1575. doi: 10.1016/j.eats.2020.06.022. eCollection 2020 Oct.


DOI:10.1016/j.eats.2020.06.022
PMID:33134062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7587500/
Abstract

Rotator cuff tears are among the most common orthopaedic conditions, with a very high social impact. A major concern is failure rates. To reduce these rates, recent years have seen increased attention to the biological augmentation of rotator cuff tears repairs, with a special focus on the application of mesenchymal stem cells (MSCs). Among the many tissues recognized as a source of MSCs, subacromial bursa recently has emerged. Another promising cell source was found to be the long head of the biceps tendon. Both those local MSC sources, unfortunately, are commonly considered discharge material. The purpose of this paper is to describe a simple yet fast arthroscopic technique of biological augmentation for rotator cuff repairs by mechanical harvesting and deployment of local MSCs sources, called LASCA (local autologous stem cells application), a feasible technique accessible to every shoulder surgeon and adaptable to many different techniques.

摘要

肩袖撕裂是最常见的骨科病症之一,具有非常高的社会影响。一个主要问题是失败率。为了降低这些比率,近年来人们越来越关注肩袖撕裂修复的生物增强,特别关注间充质干细胞(MSCs)的应用。在被认为是MSCs来源的众多组织中,肩峰下滑囊最近崭露头角。另一个有前景的细胞来源是肱二头肌长头肌腱。不幸的是,这两种局部MSCs来源通常都被视为排出物。本文的目的是描述一种简单而快速的关节镜技术,通过机械采集和部署局部MSCs来源来进行肩袖修复的生物增强,称为LASCA(局部自体干细胞应用),这是一种可行的技术,每个肩部外科医生都可以使用,并且可以适应许多不同的技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/dbc292096b91/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/ead2bd257e79/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/354091f8d702/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/a13adcedc2fb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/51a7ae1309fb/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/dbc292096b91/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/ead2bd257e79/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/354091f8d702/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/a13adcedc2fb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/51a7ae1309fb/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211f/7587500/dbc292096b91/gr5.jpg

相似文献

[1]
Local Autologous Stem Cells Application in Rotator Cuff Repairs: "LASCA" Technique.

Arthrosc Tech. 2020-10-16

[2]
Isolation and characterization of human mesenchymal stem cells derived from shoulder tissues involved in rotator cuff tears.

Am J Sports Med. 2013-1-31

[3]
Biologic augmentation of rotator cuff repair with microfragmented autologous subacromial bursal tissue enveloped in a patch of compressed autologous long head of biceps tendon tissue: the technique.

JSES Int. 2024-5-6

[4]
The Role of Mesenchymal Stem Cells in Augmenting Rotator Cuff Repairs.

Bull Hosp Jt Dis (2013). 2018-12

[5]
Biological Augmentation With Subacromial Bursa in Arthroscopic Rotator Cuff Repair.

Arthrosc Tech. 2019-7-4

[6]
Editorial Commentary: Subacromial Bursa-Friend or Foe Within The Shoulder? An Old Debate With New Insights.

Arthroscopy. 2019-11

[7]
Transtendon arthroscopic repair of high grade partial-thickness articular surface tears of the rotator cuff with biceps tendon augmentation: technical note and preliminary results.

Arch Orthop Trauma Surg. 2011-8-13

[8]
Biologic Augmentation of Arthroscopic Rotator Cuff Repair Using Minced Autologous Subacromial Bursa.

Arthrosc Tech. 2020-10-22

[9]
[Use of cultured human autologous bone marrow stem cells in repair of a rotator cuff tear: preliminary results of a safety study].

Acta Chir Orthop Traumatol Cech. 2015

[10]
Experimental rotator cuff repair. A preliminary study.

J Bone Joint Surg Am. 1999-9

引用本文的文献

[1]
Partial-Thickness Bursal-Site Rotator Cuff Repair With Autologous Bursa Augmentation.

Arthrosc Tech. 2025-5-7

[2]
The role of injections of mesenchymal stem cells as an augmentation tool in rotator cuff repair: a systematic review.

JSES Rev Rep Tech. 2025-1-13

[3]
Biologic augmentation of rotator cuff repair with microfragmented autologous subacromial bursal tissue enveloped in a patch of compressed autologous long head of biceps tendon tissue: the technique.

JSES Int. 2024-5-6

[4]
Advances in Stem Cell Therapies for Rotator Cuff Injuries.

Front Bioeng Biotechnol. 2022-5-25

[5]
Subacromial Bursa: A Neglected Tissue Is Gaining More and More Attention in Clinical and Experimental Research.

Cells. 2022-2-14

[6]
Analysis of Patient Factors Affecting In Vitro Characteristics of Subacromial Bursal Connective Tissue Progenitor Cells during Rotator Cuff Repair.

J Clin Med. 2021-9-4

本文引用的文献

[1]
Comparison of Preparation Techniques for Isolating Subacromial Bursa-Derived Cells as a Potential Augment for Rotator Cuff Repair.

Arthroscopy. 2019-11-7

[2]
Biological Augmentation With Subacromial Bursa in Arthroscopic Rotator Cuff Repair.

Arthrosc Tech. 2019-7-4

[3]
Regenerative medicine in rotator cuff injuries.

Biomed Res Int. 2014

[4]
Biologic augmentation of rotator cuff repair with mesenchymal stem cells during arthroscopy improves healing and prevents further tears: a case-controlled study.

Int Orthop. 2014-9

[5]
Multipotent mesenchymal stem cells from human subacromial bursa: potential for cell based tendon tissue engineering.

Tissue Eng Part A. 2013-8-21

[6]
Isolation and characterization of 2 new human rotator cuff and long head of biceps tendon cells possessing stem cell-like self-renewal and multipotential differentiation capacity.

Am J Sports Med. 2013-2-7

[7]
Isolation and characterization of human mesenchymal stem cells derived from shoulder tissues involved in rotator cuff tears.

Am J Sports Med. 2013-1-31

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