Dei Giudici Luca, Castricini Roberto
Orthopedic Unit, Casa di Cura "Villa Igea" Hospital, Ancona (AN), Italy.
Arthrosc Tech. 2020 Oct 16;9(10):e1571-e1575. doi: 10.1016/j.eats.2020.06.022. eCollection 2020 Oct.
Rotator cuff tears are among the most common orthopaedic conditions, with a very high social impact. A major concern is failure rates. To reduce these rates, recent years have seen increased attention to the biological augmentation of rotator cuff tears repairs, with a special focus on the application of mesenchymal stem cells (MSCs). Among the many tissues recognized as a source of MSCs, subacromial bursa recently has emerged. Another promising cell source was found to be the long head of the biceps tendon. Both those local MSC sources, unfortunately, are commonly considered discharge material. The purpose of this paper is to describe a simple yet fast arthroscopic technique of biological augmentation for rotator cuff repairs by mechanical harvesting and deployment of local MSCs sources, called LASCA (local autologous stem cells application), a feasible technique accessible to every shoulder surgeon and adaptable to many different techniques.
肩袖撕裂是最常见的骨科病症之一，具有非常高的社会影响。一个主要问题是失败率。为了降低这些比率，近年来人们越来越关注肩袖撕裂修复的生物增强，特别关注间充质干细胞（MSCs）的应用。在被认为是MSCs来源的众多组织中，肩峰下滑囊最近崭露头角。另一个有前景的细胞来源是肱二头肌长头肌腱。不幸的是，这两种局部MSCs来源通常都被视为排出物。本文的目的是描述一种简单而快速的关节镜技术，通过机械采集和部署局部MSCs来源来进行肩袖修复的生物增强，称为LASCA（局部自体干细胞应用），这是一种可行的技术，每个肩部外科医生都可以使用，并且可以适应许多不同的技术。
