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CD34表达与人类脐带血制品中的免疫表型干细胞或祖细胞含量无关。

CD34 expression does not correlate with immunophenotypic stem cell or progenitor content in human cord blood products.

作者信息

Mantri Sruthi, Reinisch Andreas, Dejene Beruh T, Lyell Deirdre J, DiGiusto David L, Agarwal-Hashmi Rajni, Majeti Ravindra, Weinberg Kenneth I, Porteus Matthew H

机构信息

Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics.

Division of Hematology, Department of Medicine, and.

出版信息

Blood Adv. 2020 Nov 10;4(21):5357-5361. doi: 10.1182/bloodadvances.2020002891.

DOI:10.1182/bloodadvances.2020002891
PMID:33136125
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7656928/
Abstract

The CD34 compartment of human cord blood contains a range of HSPC immunophenotypes, among which the LinCD34CD38CD127 CLP is rare. There is no correlation between the frequencies of CD34 cells and immunophenotypic HSC in umbilical cord blood products.

摘要

人类脐带血的CD34细胞群包含一系列造血干细胞免疫表型，其中Lin-CD34+CD38-CD127+共同淋巴祖细胞很少见。脐带血产品中CD34细胞频率与免疫表型造血干细胞之间没有相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeed/7656928/2f289804de22/advancesADV2020002891absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeed/7656928/2f289804de22/advancesADV2020002891absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeed/7656928/2f289804de22/advancesADV2020002891absf1.jpg

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Heterogeneity and hierarchy of hematopoietic stem cells.造血干细胞的异质性和层级性。
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Hematopoiesis: a human perspective.造血：人类视角。
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