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多不饱和脂肪酸与微生物群的关系:对癌症发生和治疗的影响

Polyunsaturated Fatty Acids and Microbiota Relationship: Implications in Cancer Onset and Treatment.

作者信息

Costantini Lara, Merendino Nicolò

机构信息

Department of Ecological and Biological Sciences (DEB), Tuscia University, Largo dell'Università snc, 01100 Viterbo, Italy.

出版信息

J Clin Med. 2020 Oct 29;9(11):3490. doi: 10.3390/jcm9113490.

DOI:10.3390/jcm9113490
PMID:33137937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7692308/
Abstract

In these recent years, a growing interest with regard to polyunsaturated fatty acids (PUFAs) and microbiota relationship has been noted [...].

摘要

近年来,人们对多不饱和脂肪酸(PUFAs)与微生物群的关系越来越感兴趣[……]。

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mBio. 2020 Feb 18;11(1):e03186-19. doi: 10.1128/mBio.03186-19.
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Association between blood omega-3 polyunsaturated fatty acids and the gut microbiota among breast cancer survivors.乳腺癌幸存者血液中 ω-3 多不饱和脂肪酸与肠道微生物群的关系。
Benef Microbes. 2019 Oct 14;10(7):751-758. doi: 10.3920/BM2019.0034. Epub 2019 Sep 16.
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Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids.肠道微生物群通过代谢饮食中的多不饱和脂肪酸赋予宿主抵抗肥胖的能力。
Nat Commun. 2019 Sep 5;10(1):4007. doi: 10.1038/s41467-019-11978-0.
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Multi-omic analysis in transgenic mice implicates omega-6/omega-3 fatty acid imbalance as a risk factor for chronic disease.多组学分析在转基因小鼠中表明,ω-6/ω-3 脂肪酸失衡是慢性病的一个风险因素。
Commun Biol. 2019 Jul 26;2:276. doi: 10.1038/s42003-019-0521-4. eCollection 2019.
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The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice.肠道微生物群促进小鼠肝脏脂肪酸的去饱和和延长。
Nat Commun. 2018 Sep 14;9(1):3760. doi: 10.1038/s41467-018-05767-4.
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