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用于铁检测和细胞成像的水溶性二硫化钼量子点的高产制备

High-Yield Production of Water-Soluble MoS Quantum Dots for Fe Detection and Cell Imaging.

作者信息

Xu Benhua, Zhang Zhiqi, Zhang Peng, Wang Li, Yuan Rui, Ju Zhenghua, Liu Weisheng

机构信息

Chemical Engineering College, Qinghai University, Xining 810016, China.

Qinghai Provincial Engineering Research Center of High-Performance Light Metal Alloys and Forming, Qinghai Provincial Key Laboratory of New Light Alloys, Qinghai University, Xining 810016, China.

出版信息

Nanomaterials (Basel). 2020 Oct 29;10(11):2155. doi: 10.3390/nano10112155.

DOI:10.3390/nano10112155
PMID:33137974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7692859/
Abstract

Uniform water-soluble MoS quantum dots (WS-MSQDs) were synthesized via a sequential combination of sintering/etching/exfoliation method and solvothermal route. The obtained WS-MSQDs with average size of approximately 3.4 nm exhibited sufficient water solubility and remarkable fluorescence properties. The WS-MSQDs were utilized as a probe for detection of Fe ions with high selectivity and specificity. Furthermore, the WS-MSQDs exhibited high fluorescence stability under different conditions. Finally, the WS-MSQDs were successfully applied for the fluorescence imaging of Fe in living cells, which exhibited practical potential for biomedical applications.

摘要

通过烧结/蚀刻/剥离法和溶剂热法的顺序组合合成了均匀的水溶性二硫化钼量子点（WS-MSQDs）。所获得的平均尺寸约为3.4 nm的WS-MSQDs表现出足够的水溶性和显著的荧光特性。WS-MSQDs被用作检测铁离子的探针，具有高选择性和特异性。此外，WS-MSQDs在不同条件下表现出高荧光稳定性。最后，WS-MSQDs成功应用于活细胞中铁的荧光成像，在生物医学应用中显示出实际潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/4caccdc7d3b4/nanomaterials-10-02155-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/f7cecf6346d1/nanomaterials-10-02155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/cbf8ecac5983/nanomaterials-10-02155-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/3069c95c6427/nanomaterials-10-02155-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/977ae6acede1/nanomaterials-10-02155-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/d16efaf088ce/nanomaterials-10-02155-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/69fc04b8680c/nanomaterials-10-02155-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/4caccdc7d3b4/nanomaterials-10-02155-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/f7cecf6346d1/nanomaterials-10-02155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/cbf8ecac5983/nanomaterials-10-02155-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/3069c95c6427/nanomaterials-10-02155-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/977ae6acede1/nanomaterials-10-02155-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/d16efaf088ce/nanomaterials-10-02155-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/69fc04b8680c/nanomaterials-10-02155-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c226/7692859/4caccdc7d3b4/nanomaterials-10-02155-g007.jpg

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