γ-谷维素的生物学和药理学作用：分子机制的最新综述
Biological and Pharmacological Effects of Gamma-oryzanol: An Updated Review of the Molecular Mechanisms.
机构信息
Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
出版信息
Curr Pharm Des. 2021;27(19):2299-2316. doi: 10.2174/1381612826666201102101428.
BACKGROUND
Gamma-oryzanol (γ-oryzanol) is one of the rice bran oil (RBO) compounds, known as a principal food source throughout the world. In recent numerous experimental studies, γ-oryzanol has been revealed to have several useful pharmacological properties, such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, ameliorating unpleasant menopausal symptoms, cholesterol-lowering, improving plasma lipid pattern, etc. Methods: In this study, we reviewed the scientific literature published up until 2020, which has evaluated the biological and pharmacological activity of gamma-oryzanol. This review summarizes the published data found in PubMed, Science Direct, and Scopus.
RESULTS AND CONCLUSION
The present review attempts to summarize the most related articles about the pharmacological and therapeutic potential from recent studies on γ-oryzanol to gain insights into design further studies to achieve new evidence that confirm the observed effects.
背景
γ-谷维素（γ-oryzanol）是米糠油（RBO）中的一种化合物，是全世界主要的食物来源。在最近的大量实验研究中，γ-谷维素已被证明具有多种有用的药理学特性，如抗氧化、抗炎、抗癌、抗糖尿病、改善更年期不适症状、降低胆固醇、改善血浆脂质模式等。
方法
本研究回顾了截至 2020 年发表的科学文献，这些文献评估了γ-谷维素的生物学和药理学活性。本综述总结了在 PubMed、Science Direct 和 Scopus 上找到的已发表数据。
结果与结论
本综述试图总结关于γ-谷维素的药理学和治疗潜力的最相关文章，以深入了解进一步研究的设计，以获得新的证据来证实观察到的效果。
Zotero 插件