马达加斯加农村地区潜伏性结核感染的流行率。
Latent tuberculosis infection prevalence in rural Madagascar.
机构信息
Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH 44106, USA.
Institut Pasteur de Madagascar, Ambatofotsikely, Antananarivo 101, Madagascar.
出版信息
Trans R Soc Trop Med Hyg. 2020 Nov 6;114(11):883-885. doi: 10.1093/trstmh/traa054.
Abstract
BACKGROUND
Understanding latent Mycobacterium tuberculosis infection (LTBI) prevalence is crucial for the design of TB control strategies. There are no data on LTBI in rural Madagascar.
METHODS
Tuberculin skin tests were performed in 98 adults aged >15 y in five rural villages in the Ifanadiana district, Madagascar.
RESULTS
Of adults, 78.6% were positive for LTBI, ranging between 28.6% and 95.0% among villages. The majority (65.3%) showed an induration reaction of >15 mm.
CONCLUSIONS
LTBI prevalence is high in rural Madagascar. Long-term TB control strategies including LTBI testing and treatment must account for high and heterogeneous prevalence in remote, underdeveloped areas.
摘要
背景
了解潜伏性结核分枝杆菌感染 (LTBI) 的流行率对于制定结核病控制策略至关重要。马达加斯加农村地区尚无 LTBI 数据。
方法
在马达加斯加伊法迪阿纳区的五个农村村庄中，对 98 名年龄大于 15 岁的成年人进行了结核菌素皮肤试验。
结果
成年人中，78.6%呈 LTBI 阳性，各村庄的阳性率在 28.6%至 95.0%之间。大多数（65.3%）表现出大于 15 毫米的硬结反应。
结论
马达加斯加农村地区的 LTBI 流行率很高。包括 LTBI 检测和治疗在内的长期结核病控制策略必须考虑到偏远和欠发达地区的高异质性流行率。
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