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治疗后癌症幸存者的症状体验:与接受和承诺疗法结构的关联。

Symptom experiences in post-treatment cancer survivors: associations with acceptance and commitment therapy constructs.

机构信息

Department of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.

Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

出版信息

Support Care Cancer. 2021 Jul;29(7):3487-3495. doi: 10.1007/s00520-020-05854-7. Epub 2020 Nov 2.

Abstract

PURPOSE

Acceptance and Commitment Therapy (ACT) has improved symptom and quality-of-life outcomes in pilot research with post-treatment cancer survivors. To further test the ACT model, the present study examined relationships between ACT constructs and subgroups of post-treatment survivors based on the severity of common symptoms.

METHODS

Survivors who had completed primary treatment for stage I or II cancer (N = 203) participated in this one-time survey. Latent class analysis (LCA) was used to identify subgroups of survivors based on the severity of fatigue, sleep disturbance, pain, anxiety, and depressive symptoms. Multinomial logistic regressions employing Vermunt's 3-step approach were used to examine ACT constructs (e.g., mindfulness, acceptance, values progress) as correlates of survivor subgroups based on symptoms.

RESULTS

The LCA showed three survivor classes: (1) mild-to-moderate levels of all symptoms except for normal pain intensity; (2) mild anxiety, moderate fatigue, and normal levels of all other symptoms; and (3) normal levels of all symptoms. Lower mindfulness, acceptance, and values progress and higher cognitive fusion, psychological inflexibility, and values obstruction were associated with a greater likelihood of being in class 1 or 2 than in class 3.

CONCLUSION

Findings are consistent with the ACT model. Survivors with greater symptom burden reported greater withdrawal from personally meaningful activities and less acceptance of their cancer diagnosis and internal experiences (e.g., thoughts, feelings, symptoms). Findings provide strong justification for further testing of ACT to reduce symptom-related suffering in cancer survivors.

摘要

目的

接受与承诺疗法(ACT)已在针对治疗后癌症幸存者的初步研究中改善了症状和生活质量的结果。为了进一步检验 ACT 模型,本研究根据常见症状的严重程度,检验了 ACT 结构与治疗后幸存者亚组之间的关系。

方法

本研究纳入了已完成 I 期或 II 期癌症的初级治疗(N=203)的幸存者,参与了此次一次性调查。采用潜在类别分析(LCA),根据疲劳、睡眠障碍、疼痛、焦虑和抑郁症状的严重程度,确定幸存者亚组。采用 Vermunt 的 3 步方法进行的多项逻辑回归,检验了 ACT 结构(例如,正念、接纳、价值观进展)与基于症状的幸存者亚组的相关性。

结果

LCA 显示了 3 个幸存者亚组:(1)除正常疼痛强度外,所有症状均为轻度至中度;(2)轻度焦虑、中度疲劳,以及所有其他症状均处于正常水平;(3)所有症状均处于正常水平。较低的正念、接纳和价值观进展,以及较高的认知融合、心理僵化和价值观阻碍,与属于第 1 或第 2 亚组的可能性大于第 3 亚组相关。

结论

研究结果与 ACT 模型一致。症状负担较重的幸存者更倾向于回避对个人有意义的活动,对癌症诊断和自身内部体验(例如,想法、感受、症状)的接纳程度较低。研究结果为进一步测试 ACT 以减轻癌症幸存者的症状相关痛苦提供了强有力的依据。

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