Al-Nawaiseh Ali M, Pritchett Robert C, Pritchett Kelly Kerr, Bataineh Mo'ath F, Taifour Akef M, Bellar David, Schoeff Makenzie A, Fox Brian, Judge Amy, Judge Lawrence W
Department of Sport Rehabilitation, The Hashemite University, Az-Zarqa, Jordan.
Central Washington University, Ellensburg, Washington, USA.
Int J Vitam Nutr Res. 2022 Oct;92(5-6):357-365. doi: 10.1024/0300-9831/a000683. Epub 2020 Nov 4.
Caffeine has documented hypoalgesic effects during exercise. However, there is a lack of research focusing on caffeine's potential analgesic effects to ameliorate delayed onset muscle soreness. A placebo controlled randomized cross-over trial was carried out to determine if 5 mg/kg of body weight (mg/kgBW) of caffeine attenuates muscle pain and improves 5 k running performance following delayed onset muscle soreness. Prior to participating, eleven runners (9 male; 2 female; age, 24.5 ± 6.3 years; height, 173.6 ± 7.8 cm; body mass, 66.3 ± 7.5 kg; BMI, 23.18 kg/m ± 1.6; VO 61.0 ± 6.1 ml/kg/min), were asked to discontinue supplement use for 72 hours and abstain from caffeine consumption for 48 hours. Participants performed a 30-minute downhill run on a treadmill set at -10% grade at 70% VO to induce delayed onset of muscle soreness. Participants then returned 48 hours after to complete a 5 k time trial run where they consumed either 5 mg/kgBW of caffeine or a placebo. Rate of perceived exertion and heart rate were taken every two minutes during the trial. There was no detectable statistical difference between 5 k performance between caffeine (1074.9 ± 119.7 sec) or placebo (1053.8 ± 86.8 sec) ( = .41). Algometer readings were similar between both treatments for muscle soreness in the rectus femoris ( = .791) and the vastus medialis oblique ( = .371). Muscle soreness ratings were found to be greater in the caffeine condition compared to the placebo condition ( = .030). There was no effect of treatment on rating of perceived exertion between conditions ( = .574). The present study suggests that caffeine is not effective at reducing muscle soreness, rating of perceived exertion, or improving running performance in a time trial in the presence of muscle soreness.
咖啡因在运动过程中的镇痛作用已有文献记载。然而，缺乏关于咖啡因缓解延迟性肌肉酸痛的潜在镇痛作用的研究。进行了一项安慰剂对照的随机交叉试验，以确定5毫克/千克体重（mg/kgBW）的咖啡因是否能减轻肌肉疼痛，并在延迟性肌肉酸痛后提高5公里跑步成绩。在参与试验前，11名跑步者（9名男性；2名女性；年龄24.5±6.3岁；身高173.6±7.8厘米；体重66.3±7.5千克；体重指数23.18千克/米±1.6；最大摄氧量61.0±6.1毫升/千克/分钟）被要求停止补充剂使用72小时，并在48小时内避免摄入咖啡因。参与者在坡度为-10%、速度为最大摄氧量70%的跑步机上进行30分钟的下坡跑，以诱发延迟性肌肉酸痛。然后，参与者在48小时后返回，完成一次5公里计时赛，期间他们摄入5毫克/千克体重的咖啡因或安慰剂。在试验过程中，每两分钟记录一次主观用力程度和心率。咖啡因组（1074.9±119.7秒）和安慰剂组（1053.8±86.8秒）的5公里成绩之间没有可检测到的统计学差异（P = 0.41）。两种处理方法对股直肌（P = 0.791）和股内侧斜肌（P = 0.371）肌肉酸痛的痛觉计读数相似。发现咖啡因组的肌肉酸痛评分高于安慰剂组（P = 0.030）。不同条件下，处理方法对主观用力程度评分没有影响（P = 0.574）。本研究表明，在存在肌肉酸痛的情况下，咖啡因在减轻肌肉酸痛、主观用力程度评分或提高计时赛跑步成绩方面无效。
