Weyman-Daum M, Fort P, Recker B, Lanes R, Lifshitz F
Department of Pediatrics, North Shore University Hospital, Manhasset, NY 11030.
Am J Clin Nutr. 1987 Nov;46(5):798-803. doi: 10.1093/ajcn/46.5.798.
To examine the effects of various carbohydrate foods on postprandial glycemia in diabetic children, we fed a mixed, isocaloric diet containing either high- or low-glycemic-index (GI) breakfast foods to 22 children with poorly controlled insulin-dependent diabetes mellitus (IDDM) and measured blood sugar response with and without adjustment of insulin doses. We found that IDDM children fed a high-GI meal showed a significantly higher serum glucose level than those fed a low-GI meal. However, such differences were not seen when the preprandial dose of regular insulin was adjusted to the amount of carbohydrate in feedings. Thus, as long as proper adjustment of insulin is made, the type of carbohydrate in a single mixed meal does not appear to have a significant effect on the postprandial glycemic response in children with long-standing poorly controlled IDDM.
为研究不同碳水化合物食物对糖尿病儿童餐后血糖的影响，我们给22名胰岛素依赖型糖尿病（IDDM）控制不佳的儿童喂食了含高血糖生成指数（GI）或低血糖生成指数早餐食物的混合等热量饮食，并在调整或不调整胰岛素剂量的情况下测量了血糖反应。我们发现，喂食高GI餐的IDDM儿童的血清葡萄糖水平显著高于喂食低GI餐的儿童。然而，当将餐前常规胰岛素剂量调整至进食中的碳水化合物量时，未观察到此类差异。因此，只要对胰岛素进行适当调整，单一混合餐中的碳水化合物类型似乎对长期控制不佳的IDDM儿童的餐后血糖反应没有显著影响。
